• BACKGROUND Nearly a fifth of the world’s population suffer from migraine headache, yet risk factors for this disease are poorly characterized. METHODS To further elucidate these factors, we conducted a genetic correlation analysis using cross-trait linkage disequilibrium (LD) score regression between migraine headache and 47 traits from the UK…[Read more]

  • e most promising candidate; hence, more detailed preclinical investigations with this radioligand are warranted in view of a clinical translation. © The author(s).Rationale Autophagy in Schwann cells (SCs) is crucial for myelin debris degradation and clearance following peripheral nerve injury (PNI). Nerve growth factor (NGF) plays an important…[Read more]

  • Human perception of a visual scene is hierarchically organized. Such rapid, albeit coarse, global processing allows people to create a useful context in which local details can be successively allocated. Lack of the typical hierarchical global-to-local visual processing is longitudinally predictive of future reading difficulties in pre-readers,…[Read more]

  • Background Few cases with fistulous communication between the GI system and female adnexal structure have been reported in the literature, and bilateral contrast spillage has been reported only in one case, and this case is the second one all over the world. Case presentation The case was a 27-year-old woman with a diagnosis of primary…[Read more]

  • Background As one of the novel therapeutic drugs that targets Calcitonin gene-related peptide (CGRP), 75 mg rimegepant has been used for the acute management of migraine, which is one of the most common neurological diseases worldwide. Several clinical trials have been conducted to investigate the efficacy and safety of rimegepant for the acute…[Read more]

  • A red-pigmented bacterial strain, designated KIGAM108T, within the family Hymenobacteraceae was isolated from zeolite in the Gampo-41 mine of the Gyeongju, Republic of Korea. This strain was a Gram-negative, strictly aerobic, non-spore forming, rod-shaped bacterium. Phylogenetic analysis of the 16S rRNA gene sequence of strain KIGAM108T found that…[Read more]

  • 01). After NSBB, RPP dropped below the threshold of renal flow autoregulation in 11 of the 20 (55%) RA patients, including the 4 fulfilling HRS-AKI criteria. Conclusion Renal perfusion and function depend critically of systolic function and sympathetic hyperactivation in RA. NSBB blunt the sympathetic overdrive on cardiac function, hamper cardiac…[Read more]

  • 01). After NSBB, RPP dropped below the threshold of renal flow autoregulation in 11 of the 20 (55%) RA patients, including the 4 fulfilling HRS-AKI criteria. Conclusion Renal perfusion and function depend critically of systolic function and sympathetic hyperactivation in RA. NSBB blunt the sympathetic overdrive on cardiac function, hamper cardiac…[Read more]

  • Ameloblastella martinae n. sp. is described from the gills of the pimelodid catfishes (Siluriformes Pimelodidae) Sorubim lima (Bloch & Schneider) (type-host) and Hemisorubim platyrhynchos (Valenciennes) in the Peruvian Amazonia, and on Pseudoplatystoma corruscans (Spix & Agassiz) and P. recticulatum Eigenmann & Eigenmann in Argentina. The new…[Read more]

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