Medlin Cain

Background Patient navigation is increasingly being used by pediatric health care delivery systems to address patients’ unmet social needs. However, it is not known whether navigators working remotely can be as effective at linking families to community resources as on-site navigators. The aim of this study was to assess whether a patient…[Read more]

ides reliable clues for understanding the roles of PIAS4 in the regulation of BVDV growth.BACKGROUND Environmental organic dust exposures enriched in Toll-like receptor (TLR) agonists can reduce allergic asthma development but are associated with occupational asthma and chronic bronchitis. The TLR adaptor protein myeloid differentiation factor88…[Read more]

Our study confirms that PD patients present deficits in cognitive components of ToM and preserved performances in the affective ones in early stages of disease. We also find a significant effect of dopaminergic therapy on ToM already after 3 months with a good persistency after 1 year of treatment.The current study, based on a survey of 1799…[Read more]

Vanadium slag contains high contents of vanadium and chromium with complex and dense structures, hence microwave heating instead of conventional methods is expected to destroy the dense structure and further to improve the extraction rate of vanadium and chromium, and exploring its dielectric properties is the prerequisite work. Microwave…[Read more]

Copper induces an oxidative stress condition in the marine alga Ulva compressa that is due to the production of superoxide anions and hydrogen peroxide, mainly in organelles. The increase in hydrogen peroxide is accompanied by increases in intracellular calcium and nitric oxide, and there is a crosstalk among these signals. The increase in…[Read more]

Finally, a docking study was also performed using MTB DNA Gyrase (PDB ID 5BS8) for the significantly active compound 8a to know the exact binding pattern within the active site of the target enzyme.Indole-benzimidazoles have recently gained attention due to their antiproliferative and antiestrogenic effects. However, their structural similarities…[Read more]

The Sonic Hedgehog (SHH) pathway plays a key role in cancer. Alterations of SHH canonical signaling, causally linked to tumor progression, have become rational targets for cancer therapy. However, Smoothened (Smo) inhibitors have failed to show clinical benefit in patients with cancers displaying SHH autocrine/paracrine expression. We reported…[Read more]