• Our datasets predict the expression profiles of an exceptional number of genes and allow hypotheses to be generated about the spatial organization of physiological processes. Moreover, we demonstrate that information about gene expression in a broad range of mature plant tissues can be established at high spatial resolution by nuclear mRNA…[Read more]

  • Contreras Appel posted an update 6 months ago

    In order to save water and reduce the cost of water in public areas, we studied the feasibility of recycling bath wastewater by a membrane bioreactor (MBR) at a college campus scale. The results showed that the treatment of bath wastewater by the MBR could achieve a chemical oxygen demand (COD) less then 50 mg/L with an average removal rate of…[Read more]

  • Contreras Appel posted an update 6 months ago

    LSD1 plays a pivotal role in numerous biological functions. The overexpression of LSD1 is reported to be associated with different malignancies. Over the last decade, LSD1 has emerged as an interesting target for the treatment of acute myeloid leukaemia (AML). Numerous researchers have designed, synthesized, and evaluated various LSD1 inhibitors…[Read more]

  • Contreras Appel posted an update 6 months ago

    Here, the authors describe how they manage PPH in their departments, according to the Italian guidelines, along with the addition of a ROTEM- and a TEG-guided algorithms developed by themselves.

    Although the proposed algorithms have not been validated by trials or observational studies conducted in our departments, we believe that these…[Read more]

  • Linking records from the National Spinal Cord Injury Model Systems (SCIMS) database to the National Trauma Data Bank (NTDB) provides a unique opportunity to study early variables in predicting long-term outcomes after traumatic spinal cord injury (SCI). The public use data sets of SCIMS and NTDB are stripped of protected health information,…[Read more]

  • Moyamoya angiopathy (MA) is a progressive cerebrovascular disease with a poorly understood pathophysiology. PP1 nmr It is mainly characterized by progressive bilateral stenosis of the terminal intracranial part of the supraclinoid internal carotid arteries and the proximal parts of the middle and anterior cerebral arteries. This results in…[Read more]

  • Contreras Appel became a registered member 6 months, 1 week ago