• (Retro) di-peptides as R-DIM-P-LF11-215 and DIM-LF11-322 with a net charge of +9 and moderate hydrophobicity exhibited the highest specific antitumor activity. Further evaluation of the peptides anticancer activity by 3D in vitro studies confirmed their higher activity and cancer specificity compared to their parent R-DIM-P-LF11, with the…[Read more]

  • Food production substantially depletes the environment in different ways, but little is known about how overall dietary patterns relate to these environmental impacts. The objective of this study was to evaluate the environmental performance of different dietary patterns among U.S. adults using life cycle assessment (LCA). A “typical” dietary…[Read more]

  • Streptococcus pneumoniae infection can lead to pneumococcal disease, a major cause of mortality in children under the age of five years. In low- and middle-income country settings where pneumococcal disease burden is high, vaccine use is low and widespread antibiotic use has led to increased rates of multi-drug resistant pneumococci.…[Read more]

  • 4 ± 1.8ºC and 34.5 ± 1.7ºC respectively;

     = 0.01), with a temperature above 34.7ºC being associated with malignancy (sensitivity 76%, specificity 80%;

     = 0.01). Temperatures detected in FISS did not differ significantly according to histologic subtype (

     = 0.91) or tumor grade (

    0.46), or between primary and recurring tumors (…[Read more]

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