Wilkerson Jamison

Our understanding of pilonidal sinus disease (PSD) is based on a paper published 29 years ago by Karydakis. Since then, surgeons have been taught that hair more easily penetrates wet skin, leading to the assumption that sweating promotes PSD. This postulate, however, has never been proven. Thus we used pilocarpine iontophoresis to assess sweating…[Read more]

Parkinson’s Disease (PD) is a common neurodegenerative disease which impacts millions of people around the world. In clinical treatments, freezing of gait (FoG) is used as the typical symptom to assess PD patients’ condition. Currently, the assessment of FoG is usually performed through live observation or video analysis by doctors. Considering…[Read more]

Parkinson’s Disease (PD) is a common neurodegenerative disease which impacts millions of people around the world. In clinical treatments, freezing of gait (FoG) is used as the typical symptom to assess PD patients’ condition. Currently, the assessment of FoG is usually performed through live observation or video analysis by doctors. Considering…[Read more]

The transthyretin (TTR) amyloidoses (ATTR) are progressive, degenerative diseases resulting from dissociation of the TTR tetramer to monomers, which subsequently misfold and aggregate, forming a spectrum of aggregate structures including oligomers and amyloid fibrils. To determine whether circulating nonnative TTR (NNTTR) levels correlate with the…[Read more]

For biopsies at the patch level, the model achieved a sensitivity of 72% for dysplasia and an overall accuracy of 90%. The whole-slide-image-level model achieved a sensitivity of 90% for dysplasia and 94% overall accuracy. Grad-CAMs for all models showed activation in medically relevant tissue regions. Our deep learning models achieved high…[Read more]

mining the adaptive resilience of young children exposed to maternal depression. This is discussed in the context of differential-susceptibility theory.The majority of low field Magnetic Resonance (MR) analyses rely on T2 lifetime measurements. Modification of the T2 measurement to include a T1 dimension has made the T1-T2 measurement a very…[Read more]