Maxwell Warming

Addition of uric acid (UA) to thrombolytic therapy, although safe, showed limited efficacy in improving patients’ stroke outcome, despite alleged neuroprotective effects of UA in preclinical research. This systematic review assessed the effects of UA on brain structural and functional outcomes in animal models of ischemic stroke. We searched…[Read more]

8%) nodes had developed into suspicious LNs after a median follow-up of 44 months. Loss of the fatty hilum and peripheral or diffusedly increased vascularity were more likely to be linked to persistent suspicious LNs (P = .02 and .04, respectively). Suspicious LNs with echogenic foci but a lack of other abnormal features were more frequently f…[Read more]

Carbapenems are a class of antimicrobial agents reserved for infections caused by multidrug-resistant microorganisms. The emergence of carbapenem resistance has become a serious public health threat. This type of antimicrobial resistance is spreading at an alarming rate, resulting in major outbreaks and treatment failure of community-acquired and…[Read more]

Dissipative particle dynamics (DPD) simulations was adopted to investigate the modification of polyvinylidene fluoride (PVDF) membrane by adding zwitterionic polymer brush poly(sulfobetaine methacrylate)- tetraethyl orthosilicate (PSBMA-TEOS) grafted silicon nanoparticles (SNPs) to the casting solution. The effects of polymer concentration and…[Read more]

Dissipative particle dynamics (DPD) simulations was adopted to investigate the modification of polyvinylidene fluoride (PVDF) membrane by adding zwitterionic polymer brush poly(sulfobetaine methacrylate)- tetraethyl orthosilicate (PSBMA-TEOS) grafted silicon nanoparticles (SNPs) to the casting solution. The effects of polymer concentration and…[Read more]

Bats have extensive species diversity and the residues for RBD binding in bACE2 receptor varied substantially among different bat species. Notably, the Y41H mutant, which exists in many bats, attenuates the binding capacity of bACE2-Rm, indicating the central roles of Y41 in the interaction network. These findings would benefit our understanding…[Read more]