• Emerson Grau posted an update 6 months, 2 weeks ago

    The new version of COMPASS, improved by taking into account the participants’ comments and suggestions, was more usable than the initial version.Neck injuries and pathologies are widespread and cause disability. Clinicians use different tools to measure the cervical spine’ mobility to diagnose different disorders. There are many reliable assessment methods for this purpose, but their benefits have not been deeply investigated and compared, as well as their measurement results. This review aims to summarise the advantages, accuracy, and reliability, of measurement tools and devices used in studies or trails related to the neck and cervical spine evaluation, to evidence the use of inertial sensors and compare them, to highlight the best assessment systems and their characteristics. A literature review has been performed in a range of five years, to obtain information about cervical spine evaluation. Studies that met the established inclusion criteria were selected and classified according their pathology studied, objectives and methodologies followed when evaluating the cervical spine functionality. Studies were described chronologically highlighting the tools employed, where the motion capture systems and cervical range of motion devices stood out as the most used and reliable methods. Cervical spine assessment studies employing systems with inertial sensors as an accurate method, is not evidenced in the sample. However, they are widely tested and different studies validate these systems for their clinical area use, obtaining high reliability and repeatability. Thereby, this review argues that inertial sensors have proven to be a portable, and easy to use tool for the evaluation of neck and its related pathologies, with a great accuracy level.Dietary supplement use continues to increase, with athlete use surpassing non-athlete utilization. Most research has been conducted on dietary supplement use in elite or collegiate-level athletes. compound library chemical This study investigated supplement use in adult recreational runners and determined relationships between supplement use and participants’ training volume, motivations for exercise, self-reported health status, and reasons for using dietary supplements. Participants (n = 283) were recruited for this cross-sectional study via a convenience sampling method. Participants completed an electronic questionnaire using Likert-scale response options. Correlations between the aggregate variables of health status, training level, exercise motivation, reasons for using supplements, and supplement use were calculated using bivariate Pearson correlation analysis. There was a positive correlation between the variables exercise motivation and supplement use (r = 0.267, n = 276, p = 0.01), and between variables influencing reasons for using dietary supplements and reported supplement use was also found (r = 0.425, n = 276, p = 0.01). There was no correlation between health status and supplement use (r = 0.043, n = 275, p = 0.476), or between training level and supplement use (r = 0.00, n = 275, p = 0.994). This study demonstrated a positive correlation between runners’ supplement use and motivations for exercising and reasons for consuming supplements. A significant relationship was not found between supplement use and participants’ health status or supplement use and runners’ training volume. This finding contrasts with previous research in supplement use in the athlete population, which largely reports increased dietary supplement use with increased training volume.

    A growing body of literature demonstrates that survivors of congenital heart defects (CHD) are at increased risk of neurodevelopmental delay, which frequently manifests as motor delay during the first year of life.

    The aim of this study was to determine prenatal predictors of an early atypical neurodevelopment. This information could help assist decision-making during prenatal counseling.

    In this retrospective cohort study, we evaluated the records of 75 children with CHD followed at the

    (CINC) of the CHU Ste-Justine born between 2013 and 2016. The neurodevelopmental outcome was determined using the Alberta Infant Motor Scale (AIMS) at 4 months. Associations between prenatal factors and atypical neurodevelopment (AIMS < 10th percentile) were assessed using bivariate and multivariate analyses.

    Forty-four infants (58.7%) had atypical neurodevelopment. When there was no extra cardiac anomaly seen on prenatal ultrasound, a head to abdominal ratio (HC/AC) below 1.1 was associated with a four-fold incohort is needed to validate those results.Management of depression symptoms in hospice patients is complicated by the fact that an appropriate trial of antidepressant therapy requires 4-6 weeks and most hospice patients receive hospice services for less than 8 weeks. Intravenously administered ketamine has been shown to produce rapid improvement in depression symptoms but is not an ideal route for hospice patients and oral ketamine appears to have a slower onset of antidepressant activity. We present a case series that illustrates the use of a single subcutaneous dose of ketamine (0.5 mg/kg) followed by daily oral ketamine (0.5 mg/kg daily) therapy to manage depression symptoms in three hospice patients. Clinical improvement of depression symptoms occurred quickly for all patients as measured by the PHQ-4, numeric ratings, and subjective reporting. A single subcutaneous dose of ketamine followed by oral therapy presents itself as an option to quickly reduce depression symptoms in hospice patients that do not also require additional pain management. Combining the use of the subcutaneous and oral routes takes advantage of the possibly faster onset, home administration, and milder side effects than intravenous dosing. Prospective studies are needed to determine which dosing strategy would be the most beneficial for hospice patients.

    While the standard setting during radiofrequency catheter ablation (RFCA) consists of applying low power for long times, a new setting based on high power and short duration (HPSD) has recently been suggested as safer and more effective. Our aim was to compare the electrical and thermal performance of standard vs. HPSD settings, especially to assess the effect of the catheter orientation.

    A 3D computational model was built based on a coupled electric-thermal-flow problem. Standard (20 W-45 s and 30 W-30 s) and HPSD settings (70 W-7 s and 90 W-4 s) were compared. Since the model only included a cardiac tissue fragment, the power values were adjusted to 80% of the clinical values (15, 23, 53 and 69 W). Three catheter-tissue orientations were considered (90°, 45° and 0°). Thermal lesions were assessed by the Arrhenius equation. Safety was assessed by checking the occurrence of steam pops (100 °C in tissue) and thrombus formation (80 °C in blood).

    The computed thermal lesions were in close agreement with the experimental data in the literature, in particular with

    studies.

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