Ibsen Childers

Mutations that enhance LRRK2 protein kinase activity cause inherited Parkinson’s disease. LRRK2 phosphorylates a group of Rab GTPase proteins, including Rab10 and Rab12, within the effector-binding switch-II motif. Previous work has indicated that the PARK16 locus, which harbors the gene encoding for Rab29, is involved in Parkinson’s, and that…[Read more]

At the equatorial zone and anterior central zone of lens, AR expression and TUNEL-positive apoptotic LECs were significantly increased in the DM group compared with the control group, however, they were significantly decreased in the DM + NGF group. In conclusion, topical NGF could delay the progression of diabetic cataracts by attenuating polyol…[Read more]

es for innovation.

This study identified the most prevalent tracks of implementation in the literature for data preparation, methodology selection and output evaluation for various medical image analysis tasks. Also, we identified several critical research gaps existing in the TL studies on medical image analysis. The findings of this scoping…[Read more]

es for innovation.

This study identified the most prevalent tracks of implementation in the literature for data preparation, methodology selection and output evaluation for various medical image analysis tasks. Also, we identified several critical research gaps existing in the TL studies on medical image analysis. The findings of this scoping…[Read more]

We categorized these applications into four core topics, including diagnosis and prediction, treatment, protection, and management goals, which were confirmed by five experts. Without applying IT, the control and management of the crisis could be difficult on a large scale. For reducing and improving the hazard effect of disaster situations, the…[Read more]

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Identifying the factors influencing parental adaptation helps the medical staff to make the necessary interventions to support the parents. According to this study, increasing parent access to the required information, supporting them financially and emotionally, and helping them identify support resources can facilitate their adaptation…[Read more]

Timely diagnosis and management of a retrorectal mass is essential for effective treatment and to prevent subsequent complications.A 62-year-old man with a past medical history of uncontrolled hypertension, tobacco abuse, and type 2 diabetes mellitus (DM) presented to the emergency department due to worsening confusion over the last 24 hours as…[Read more]

Timely diagnosis and management of a retrorectal mass is essential for effective treatment and to prevent subsequent complications.A 62-year-old man with a past medical history of uncontrolled hypertension, tobacco abuse, and type 2 diabetes mellitus (DM) presented to the emergency department due to worsening confusion over the last 24 hours as…[Read more]

There is a paucity of data in the literature specific to men with epilepsy on anti-seizure medication (ASM). The current study investigated the time to conception as well as the gestational and the neurodevelopmental outcomes of offspring of men with epilepsy on ASM compared to controls. Additionally, the prevalence of psychiatric comorbidities,…[Read more]