• To assess temporal trends in the association between newly diagnosed atrial fibrillation and death.

    Community based cohort study.

    Framingham Heart Study cohort, in 1972-85, 1986-2000, and 2001-15 (periods 1-3, respectively), in Framingham, MA, USA.

    Participants with no atrial fibrillation, aged 45-95 in each time period,…[Read more]

  • Furthermore, the MD simulation of F-actin with the Ain1 ABD R216E indicated that the stronger affinity is caused by a direct interaction of the point mutation. Our findings might be applicable to other highly conserved ABP family proteins to explain their binding affinities.The photodissociation dynamics of CF2ICF2I in solution was investigated…[Read more]

  • 0006). Body weight gain (BWG) at the starter phase (3-4 months) was higher than the pre-starter (1-2 months) and grower (5-6 months) phases (P  less then  0.0001). The highest concentration of blood glucose was observed at 2 months of age while the lowest magnitude was found at 4 months of age (P  less then  0.0001). The plasma cholesterol concent…[Read more]

  • We report a covalent chemistry-based hepatocellular carcinoma (HCC)-specific extracellular vesicle (EV) purification system for early detection of HCC by performing digital scoring on the purified EVs. Earlier detection of HCC creates more opportunities for curative therapeutic interventions. EVs are present in circulation at relatively early…[Read more]

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