• Penn Bredahl posted an update 6 months ago

    Spectrometric analysis is one of the most widely used approaches to characterize the chemical nature of microplastics. Despite recent developments, this key step remains time consuming. The aim of this paper is to propose a new method for the pre-detection of microplastics based on mid-infrared imaging. Plastic particles were mixed with sand particles and placed on a glass filter. Infrared observation with a thermal camera shows a stronger thermal contrast measured between the filter and the plastics than between the filter and the sand, which reveals the plastic particles in a few tens of seconds. An image processing tool is then used to amplify this contrast. Furthermore, this pre-detection method makes it possible to propose hypotheses on the most probable chemical nature of the particles identified. Consequently, pre-detection using active thermography constitutes a promising way of significantly accelerating microplastic study.Microplastic (MP) pollution has spurred a wide range of concerns due to its ubiquity and potential hazards to humans and ecosystems, yet studies on MP abundance, distribution, and ecological impacts on the small-scale local estuarine systems are insufficient. We conducted the first study of MP pollution in surface water of Dongshan Bay in southern China. A total of six water samples were collected using a Manta trawl (length = 3 m, width = 1 m, height = 0.6 m, and mesh size = ∼330 μm). The abundance, type, shape, color, and size, were measured using light microscopy and micro-Raman spectroscopy. Our results showed that MPs spanned from 0.23 to 4.01 particles m-3 with an average of 1.66 particles m-3. 75% of the MPs were PP, PE, and PS that may be explained by the widespread application of PE, PP, and PS foam in local fishing and aquaculture within the bay. Foam, white, and 1.0-2.5 mm were dominant shape, color, and size of MPs, respectively. Both indices of MPs-induced risk (Hestuary = 13.7) and pollution load (PLIestuary = 14.2) yielded a Hazard Level II for MPs pollution in the Dongshan Bay. The potential ecological risk from combined MPs polymers (RIestuary = 21.5) ended up at a minor risk. Our findings established the first set of baseline data on MPs pollution in Dongshan Bay and provided preliminary quantitative measures on the scale of ecological risk, which would improve the understanding of MP fate, transport, and ecological impacts in the estuarine environment.

    Appendicitis is a common indication for urgent abdominal surgery in the pediatric population. The postoperative management varies significantly in time to discharge and cost of care. selleck compound The objective of this study was to investigate whether implementation of an evidence-based protocol after an appendectomy would lead to decreased length of stay and cost of care.

    In 2014 at the Children’s Hospital of Pittsburgh, an initiative to develop an evidenced-based protocol to treat appendicitis was undertaken. A work group was formed of pediatric surgeons and other important personnel to determine best practices. Treatment pathways were created. Pathways differed with recommendation on postoperative antibiotic choice and duration, diet initiation, and discharge criteria. Data were prospectively gathered from all patients (ages 0-18y) with acute appendicitis from January 2015 to December 2016. Primary outcomes were length of stay and cost of care. Secondary outcomes were surgical site infection, readmission rate, and duration of postoperative antibiotics.

    Among the 1289 patients, 481 patients were in the preprotocol cohort and 808 patients were in the postprotocol cohort. 27% of patients had an intraoperative diagnosis of complicated appendicitis. There was a significantly shorter length of stay in the postprotocol cohort (P<0.001). Median costs for the whole cohort decreased 0.6% and 24.6% for patients with complicated appendicitis after protocol initiation (P<0.01).

    This study has demonstrated that introduction of an evidence-based clinical care protocol for pediatric patients with appendicitis leads to shorter hospital stay and decreased hospital costs.

    This study has demonstrated that introduction of an evidence-based clinical care protocol for pediatric patients with appendicitis leads to shorter hospital stay and decreased hospital costs.

    To assess the impact of iterative reconstructions on image quality and detectability of focal liver lesions in low-energy monochromatic images from a Fast kV-Switching Dual Energy CT (KVSCT) platform.

    Acquisitions on an image-quality phantom were performed using a KVSCT for three dose levels (CTDI

    12.72/10.76/8.79mGy). Raw data were reconstructed for five energy levels (40/50/60/70/80keV) using Filtered Back Projection (FBP) and four levels of ASIR (ASIR30/ASIR50/ASIR70/ASIR100). Noise power spectrum (NPS) and task-based transfer function (TTF) were measured before computing a Detectability index (d’) to model the detection task of liver metastasis (LM) and hepatocellular carcinoma (HCC) as function of keV.

    From 40 to 70keV, noise-magnitude was reduced on average by -68%±1% with FBP; -61%±3% with ASIR50 and -52%±6% with ASIR100. The mean spatial frequency of the NPS decreased when the energy level decreased and the iterative level increased. TTF values at 50% decreased as the energy level increased and as the percentage of ASIR increased. The detectability of both lesions increased with increasing dose level and percentage of ASIR. For the LM, d’ peaked at 70keV for all reconstruction types, except for ASIR70 at 12.72mGy and ASIR100, where d’ peaked at 50keV. For HCC, d’ peaked at 60keV for FBP and ASIR30 but peaked at 50keV for ASIR50, ASIR70 and ASIR100.

    Using percentage of ASIR above 50% at low-energy monochromatic images could limit the increase of noise-magnitude, benefit from spatial resolution improvement and hence enhance detectability of subtle low contrast focal liver lesions such as HCC.

    Using percentage of ASIR above 50% at low-energy monochromatic images could limit the increase of noise-magnitude, benefit from spatial resolution improvement and hence enhance detectability of subtle low contrast focal liver lesions such as HCC.

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