• A novel coronavirus (severe acute respiratory syndrome coronavirus 2, SARS-CoV-2) causing a cluster of respiratory infections (coronavirus disease 2019, COVID-19) in Wuhan, China, was identified on 7 January 2020. TDO inhibitor The epidemic quickly disseminated from Wuhan and as at 12 February 2020, 45,179 cases have been confirmed in 25…[Read more]

  • In conclusion, T. canis larval migration activated the MMPs and caused pulmonary pathogenesis.

    These phenomena subsequently induced the activities of MMPs in parallel with the pathological changes in early stage pulmonary inflammation. In conclusion, T. canis larval migration activated the MMPs and caused pulmonary pathogenesis.

    Respiratory…[Read more]

  • BACKGROUND Coordinated interactions within central and peripheral neural networks determine the integrated autonomic response to cardiovascular stressors. Excessive sympathoexcitation in response to ischemia is a major contributor to sudden cardiac death. OBJECTIVE To define fundamental aspects of cardiac-related autonomic neural network…[Read more]

  • However, these hotspots are not necessarily the same as the area most vulnerable to climate change, because some areas that are more sensitive to heatwaves may have a higher capacity to adapt to them due to a host of factors including their population characteristics (e.g. rates of the elderly or children), socio-economic and geographical…[Read more]

  • Notably, caution should be taken when interpreting results of ROS and RNS measurements due to this dual role of free radicals in protecting and injuring the graft.Research in xenotransplantation implies a high experimental complexity comprising molecular, cellular, and in vivo studies to investigate the mechanisms of xenograft immune rejection and…[Read more]

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