Rahbek Slater

Therapeutic options for patients with treatment-resistant epilepsy represent an important unmet need. Addressing this unmet need was the main factor driving the drug discovery program that led to the synthesis of padsevonil, a first-in-class antiepileptic drug candidate that interacts with two therapeutic targets synaptic vesicle protein 2 and…[Read more]

t the interpretation, for which the vibronic transitions that were previously assigned to a slightly bent structure of the first excited state needs to be revised and that a full rationalization of the PES spectra would require the explicit inclusion of the nuclear dynamical effects, beyond the Born-Oppenheimer (BO) approximation. From a…[Read more]

Haemonchus contortus and Teladorsagia circumcincta are among the two most pathogenic internal parasitic nematodes infecting small ruminants, such as sheep and goats, and are a global animal health issue. Accurate identification and delineation of Haemonchidae species is essential for development of diagnostic and control strategies with high…[Read more]

The new C. remanei genome presented here greatly augments the use of the Caenorhabditis as a platform for comparative genomics and serves as a basis for molecular population genetics within this highly diverse species. Copyright © 2020, Genetics.The polysaccharide pectin is a major component of the plant cell wall. The pectic glycan…[Read more]

Cigarette smoking is a risk factor for several lung diseases, including chronic obstructive pulmonary disease, cardiovascular disease, and lung cancer. The potential health effects of chronic use of electronic nicotine delivery systems (ENDS) is unclear. This study utilized fully differentiated primary normal human bronchial epithelial (NHBE)…[Read more]