Connor Jernigan

A RAF-1/MEK/ERK pathway was founded to be associated with AG-221 and ATRA-induced differentiation in IDH2-mutant AML cells. IDH-associated changes in histone methylation markers decreased after AG-221 and ATRA combination treatment.

Our preliminary evidence indicates that the addition of ATRA to treatments with IDH2 inhibitor may lead to…[Read more]

Automatic sleep stage detection can be performed using a variety of input signals from a polysomnographic (PSG) recording. In this study, we investigate the effect of different input signals on the performance of feature-based automatic sleep stage classification algorithms with both a Random Forest (RF) and Multilayer Perceptron (MLP) classifier.…[Read more]

The prevailing theories describing DNA confinement in a nanochannel are predicated on the assumption that wall-DNA electrostatic interactions are sufficiently short-ranged such that the problem can be mapped to an equivalent neutral polymer confined by hard walls with an appropriately reduced effective channel size. To determine when this…[Read more]

Objective As the coronavirus pandemic extends across the globe, the impacts have been felt across domains of industry. Neuropsychology services are no exception. Methods for neuropsychological assessments, which typically require an in-person visit, must be modified in order to adhere to social distancing and isolation standards enacted in an…[Read more]

Nontargeted mass spectrometry (MS) is widely used in life sciences and environmental chemistry to investigate large sets of samples. 2,2,2Tribromoethanol A major problem for larger-scale MS studies is data gaps or missing values in aligned data sets. The main causes for these data gaps are the absence of the compound from the sample, issues…[Read more]