Nance May

A basic paradigm underlying the Hookean mechanics of amorphous, isotropic solids is that small deformations are proportional to the magnitude of external forces. However, slender bodies may undergo large deformations even under minute forces, leading to nonlinear responses rooted in purely geometric effects. Here we study the indentation of a…[Read more]

A basic paradigm underlying the Hookean mechanics of amorphous, isotropic solids is that small deformations are proportional to the magnitude of external forces. However, slender bodies may undergo large deformations even under minute forces, leading to nonlinear responses rooted in purely geometric effects. Here we study the indentation of a…[Read more]

A basic paradigm underlying the Hookean mechanics of amorphous, isotropic solids is that small deformations are proportional to the magnitude of external forces. However, slender bodies may undergo large deformations even under minute forces, leading to nonlinear responses rooted in purely geometric effects. Here we study the indentation of a…[Read more]

Repeat therapy with intraperitoneal paclitaxel has been used recently. Intraperitoneal administration of paclitaxel results in prolonged retention in the peritoneal cavity with effects against peritoneal metastases. Repeated administration of paclitaxel does not cause adhesions in the peritoneal cavity. When combination chemotherapy is effective,…[Read more]

Canonical prefoldin is a protein cochaperone composed of six different subunits (PFDN1 to 6). PFDN1 overexpression promotes epithelial-mesenchymal transition (EMT) and increases the growth of xenograft lung cancer (LC) cell lines. We investigated whether this putative involvement of canonical PFDN in LC translates into the clinic. First, the mRNA…[Read more]

Aim To develop a protocol to ensure the quality of respiratory protective devices for healthcare workers nursing and treating patients with possible or confirmed COVID-19 in the Catharina hospital. Background Due to the COVID-19 outbreak a shortage of respirators is occurring worldwide; more specifically, CE-certified FFP2 respirators. This has…[Read more]

Objective To use mathematical models to predict the epidemiological impact of lifting the lockdown in London, UK, and alternative strategies to help inform policy in the UK. Methods A mathematical model for the transmission of SARS-CoV2 in London. The model was parametrised using data on notified cases, deaths, contacts, and mobility to analyse…[Read more]

However, the peripheral neuropathy was more frequent in patients who were treated with FOLFOX (P A variant was relatively higher than other similar studies. Trial registration Approval code; IR.MAZUMS.REC.95.2480.Background The period surrounding childbirth is one of profound change, which can often be experienced as stressful and overwhelming.…[Read more]