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@hatpastry7
20
Beans
PI3Kα has been identified as an ideal target to treat with PIK3CA gene mutation disease, including drugs such as Alpelisib and Copanlisib. Five purine analogues and four thiazole analogues were designed and synthesized. Their enzymaticactivity against PI3Ka/β/γ/δ were tested, respectively. All compounds showed excellent selectivity in mod […] View
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Morgan Waugh posted an update 6 months, 3 weeks ago
PI3Kα has been identified as an ideal target to treat with PIK3CA gene mutation disease, including drugs such as Alpelisib and Copanlisib. Five purine analogues and four thiazole analogues were designed and synthesized. Their enzymaticactivity against PI3Ka/β/γ/δ were tested, respectively. All compounds showed excellent selectivity in mod…[Read more]
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Morgan Waugh became a registered member 6 months, 3 weeks ago
