Axelsen Acevedo

Here we analyze the relationships between membrane alterations induced by photo-oxidation and the biochemical responses in mammalian cells. We specifically address the impact of photosensitization reactions in membranes of different organelles such as mitochondria, lysosome, endoplasmic reticulum, and plasma membrane, and the subsequent responses…[Read more]

Smoking is associated with incident heart failure (HF), yet limited data are available exploring the association between smoking status and long-term outcomes in HF with reduced vs. preserved ejection fraction (i.e., HFrEF vs. HFpEF).

We performed a retrospective analysis of HF patients undergoing coronary angiography from 1990-2010. Patients…[Read more]

Our findings demonstrate a folded protein system in which spontaneously formed intermolecular disulfide bonds initiate amyloid fibril formation by recruitment of monomers. This dimer-induced aggregation mechanism may be of relevance for human amyloid diseases in which oxidative stress is often an associated hallmark.Land-use intensification can…[Read more]

01). Chronic suture implantation did not change pupil size, anterior chamber depth or iridocorneal angles (p>0.05). EVP was significantly higher in OHT eyes compared to control eyes (p<0.01). There was no statistical difference in C, Fu and Fin between groups (p>0.05). A significant linear correlation was found between IOP and EVP (R

=0.35,…[Read more]

naccounted confounders such as in-hospital management.

Longer prehospital time was not associated with an increased risk of 30-day mortality, but it may be associated with increased risk of poor functional outcomes in injured patients. This finding supports the concept of the “golden hour” for trauma patients during prehospital care in the…[Read more]