Pehrson Kendall

Liver malignancies are among the tumor types that are resistant to immune checkpoint inhibition therapy. Tumor-associated macrophages (TAMs) are highly enriched and play a major role in inducing immunosuppression in liver malignancies. Herein, CCL2 and CCL5 are screened as two major chemokines responsible for attracting TAM infiltration and…[Read more]

Cancer incidence is rising, and accurate prediction of incident cancers could be relevant to understanding and reducing cancer incidence. The aim of this study was to develop machine learning (ML) models that could predict an incident diagnosis of cancer. Participants without any history of cancer within the Lifelines population-based cohort were…[Read more]

Cancer incidence is rising, and accurate prediction of incident cancers could be relevant to understanding and reducing cancer incidence. The aim of this study was to develop machine learning (ML) models that could predict an incident diagnosis of cancer. Participants without any history of cancer within the Lifelines population-based cohort were…[Read more]

Cancer incidence is rising, and accurate prediction of incident cancers could be relevant to understanding and reducing cancer incidence. The aim of this study was to develop machine learning (ML) models that could predict an incident diagnosis of cancer. Participants without any history of cancer within the Lifelines population-based cohort were…[Read more]

Cancer incidence is rising, and accurate prediction of incident cancers could be relevant to understanding and reducing cancer incidence. The aim of this study was to develop machine learning (ML) models that could predict an incident diagnosis of cancer. Participants without any history of cancer within the Lifelines population-based cohort were…[Read more]

Our genomic analysis of single or purified cells, coupled with precision genetics, provides an epigenetic basis for alveolar cell fate and potential, and introduces an experimental benchmark for deciphering the in vivo function of lineage transcription factors.The classic paradigm of physical metallurgy is that the addition of alloying elements to…[Read more]

Our genomic analysis of single or purified cells, coupled with precision genetics, provides an epigenetic basis for alveolar cell fate and potential, and introduces an experimental benchmark for deciphering the in vivo function of lineage transcription factors.The classic paradigm of physical metallurgy is that the addition of alloying elements to…[Read more]

A common feature associated with fetal alcohol spectrum disorders is the inability to concentrate on a specific task while ignoring distractions. Human continuous performance tasks (CPT), measure vigilance and cognitive control simultaneously while these processes are traditionally measured separately in rodents. We recently established a…[Read more]

Binding theories postulate short-term episodic traces within which stimulus and response features are integrated. These episodic traces can influence actions by facilitating or interfering with responding. Although the existence of such short-term episodic traces has been well documented, the role of location and the organization of bindings…[Read more]

I are low. Age, baseline ALT, haemoglobin and HBsAg positivity are risk factors for the development of DILI and these inform monitoring and management of these patients.

The efficacy and safety of a fluid-filled intragastric balloon (IGB) for weight loss in cirrhotic patients on the liver-transplant waitlist is unknown.

We enrolled…[Read more]

I are low. Age, baseline ALT, haemoglobin and HBsAg positivity are risk factors for the development of DILI and these inform monitoring and management of these patients.

The efficacy and safety of a fluid-filled intragastric balloon (IGB) for weight loss in cirrhotic patients on the liver-transplant waitlist is unknown.

We enrolled…[Read more]

I are low. Age, baseline ALT, haemoglobin and HBsAg positivity are risk factors for the development of DILI and these inform monitoring and management of these patients.

The efficacy and safety of a fluid-filled intragastric balloon (IGB) for weight loss in cirrhotic patients on the liver-transplant waitlist is unknown.

We enrolled…[Read more]

01). The mean interval from IVCR implantation to initiation of ITC was 15.2 ± 8.5days and 3.3 ± 3.0days in patients who underwent CSF flow study and patients that did not, respectively (p < 0.0001).

A flow study can provide information regarding CSF flow dynamics prior to initiation of ITC; however this might delay initiation of ITC which…[Read more]

01). The mean interval from IVCR implantation to initiation of ITC was 15.2 ± 8.5days and 3.3 ± 3.0days in patients who underwent CSF flow study and patients that did not, respectively (p < 0.0001).

A flow study can provide information regarding CSF flow dynamics prior to initiation of ITC; however this might delay initiation of ITC which…[Read more]

Tenofovir-25 also failed to attenuate DMH/HFD-induced oxidative stress, whereas tenofovir-50 significantly attenuated oxidative stress as indicated by the decreased MDA concentration and SOD activity along with the increased GSH concentrations. Moreover, tenofovir-50 decreased Bcl-2 and cyclin D1 expressions in colon tissues compared with DMH/HFD…[Read more]