• Urolithin A impeded the TNFα-induced barrier loss by inhibition of claudin-1 and -2 protein expression upregulation and claudin-1 delocalization in HT-29/B6. Conclusion Ellagic acid and urolithin A affect intestinal barrier function in distinct ways. Ellagic acid acts preventive by strengthening the barrier per se, while urolithin A protects…[Read more]

  • The treatment protocol was changed to an amrubicin monotherapy regimen. However, the patient’s general condition worsened after the therapies, and he died 38 months after the surgery.Pancreatic neuroendocrine tumor(p-NET)is a relatively rare disease, and treatment is multidisciplinary with resection, local therapy, radiotherapy, and chemotherapy.…[Read more]

  • The treatment protocol was changed to an amrubicin monotherapy regimen. However, the patient’s general condition worsened after the therapies, and he died 38 months after the surgery.Pancreatic neuroendocrine tumor(p-NET)is a relatively rare disease, and treatment is multidisciplinary with resection, local therapy, radiotherapy, and chemotherapy.…[Read more]

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