Kold Cobb

Viral relapse is a major concern in hepatitis C virus (HCV) antiviral therapy. Currently, there are no satisfactory methods to predict viral relapse, especially in the era of direct acting antivirals in which the virus often quickly becomes undetectable using PCR-based approaches that focus on a small viral region. Next-generation sequencing (NGS)…[Read more]

Loss or disrupted expression of the FMR1 gene causes fragile X syndrome (FXS), the most common monogenetic form of autism in humans. Although disruptions in sensory processing are core traits of FXS and autism, the neural underpinnings of these phenotypes are poorly understood. Using calcium imaging to record from the entire brain at cellular…[Read more]

The promising result demonstrated in this work has shown great potential to employ the robust mini-SLidar system for atmospheric monitoring in the boundary layer.We experimentally demonstrate a harmonic-order controllable L-band Er-doped passively mode-locked fiber laser based on nonlinear polarization rotation (NPR). Distinct from all previous…[Read more]

27, 95% CrI, 1.08-1.11) vs diffuse subtype (TR 1.17, 95% CrI, 1.09-1.24) and the probability of increasing OS > 15% was 90% vs 67% in each subtype, respectively. The effect dwindles over time, which can be attributed to pathological changes and clinical practice changes.

Our study confirms the effect of DPF is highly dependent on sev…[Read more]