• Duffy Winkel posted an update 7 months, 3 weeks ago

    1%], and 32.4 Black ). Study 1 found that 63% to 91% of gun owners and 83% to 93% of non-gun owners supported key gun safety policies, yet both groups significantly underestimated gun owners’ support for these policies by between 12% and 31%. Studies 2 and 3 found that exposure to corrective information was associated with a small increase in support for 2 gun safety policies of between 4% and 15%, both in terms of participants’ privately held beliefs and the beliefs they would be willing to share publicly.

    This survey study found that many US adults failed to recognize that most gun owners support key gun safety policies. Correcting this misperception was associated with greater private and public support for gun safety policy.

    This survey study found that many US adults failed to recognize that most gun owners support key gun safety policies. Correcting this misperception was associated with greater private and public support for gun safety policy.

    Engaging adolescent boys and young men in preventing violence against women is a potentially impactful public health strategy.

    To evaluate the effectiveness of a community-based, gender-transformative program (ie, Manhood 2.0) on perpetration of gender-based violence by adolescent boys and young men.

    In this unblinded cluster randomized clinical trial, neighborhoods were designated as the unit of clustering (11 allocation). Three-month (ie, time point 2 ) and 9-month (ie, time point 3 ) follow-ups were conducted. The trial took place in 20 Pittsburgh, Pennsylvania, neighborhoods and 1 centrally located site with concentrated disadvantage. Pittsburgh-based adolescent boys and young men (ages 13 to 19 years) were recruited between July 27, 2015, and June 5, 2017, through youth-serving organizations and community-based alternatives to residential placement for juvenile justice-involved youth. Intention-to-treat analysis was conducted from June 2018 to November 2019.

    Manhood 2.0, an international ommunity-based efforts are needed.

    ClinicalTrials.gov Identifier NCT02427061.

    ClinicalTrials.gov Identifier NCT02427061.

    Approximately 356 000 people stay in homeless shelters nightly in the United States. They have high risk of contracting coronavirus disease 2019 (COVID-19).

    To assess the estimated clinical outcomes, costs, and cost-effectiveness associated with strategies for COVID-19 management among adults experiencing sheltered homelessness.

    This decision analytic model used a simulated cohort of 2258 adults residing in homeless shelters in Boston, Massachusetts. Cohort characteristics and costs were adapted from Boston Health Care for the Homeless Program. Disease progression, transmission, and outcomes data were taken from published literature and national databases. Surging, growing, and slowing epidemics (effective reproduction numbers , 2.6, 1.3, and 0.9, respectively) were examined. Costs were from a health care sector perspective, and the time horizon was 4 months, from April to August 2020.

    Daily symptom screening with polymerase chain reaction (PCR) testing of individuals with positive symptom screeni with further decrease in SARS-CoV-2 infections at modest incremental cost and should be considered during future surges.

    In this modeling study of simulated adults living in homeless shelters, daily symptom screening and ACSs were associated with fewer severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and decreased costs compared with no intervention. In a modeled surging epidemic, adding universal PCR testing every 2 weeks was associated with further decrease in SARS-CoV-2 infections at modest incremental cost and should be considered during future surges.

    Anti-Müllerian hormone (AMH) measured in adolescence as biomarker for prediction of adult polycystic ovary syndrome (PCOS) is doubtful but not substantiated.

    To investigate whether serum AMH levels and other PCOS-associated features in adolescence can predict the presence of PCOS in adulthood.

    A long-term follow-up study based on a unique adolescent study on menstrual irregularities performed between 1990 and 1997.

    AMH was assayed in 271 adolescent girls. Data on PCOS features were combined with AMH levels. see more In 160 of the 271 (59%) participants, we collected information in adulthood about their menstrual cycle pattern and presence of PCOS (features) by questionnaire 2 decades after the initial study.

    AMH was higher in adolescent girls with oligomenorrhea compared with girls with regular cycles, median (interquartile range) 4.6 (3.1-7.5) versus 2.6 (1.7-3.8) μg/L (P < 0.001). Women with PCOS in adulthood had a higher median adolescent AMH of 6.0 compared with 2.5 μg/L in the non-PCOS group (P < 0.001). AMH at adolescence showed an area under the receiver operating characteristic curve for PCOS in adulthood of 0.78. In adolescent girls with oligomenorrhea the proportion developing PCOS in adulthood was 22.5% (95% CI, 12.4-37.4) against 5.1% (95% CI, 2.1-12.0) in girls with a regular cycle (P = 0.005). Given adolescent oligomenorrhea, adding high AMH as factor to predict adult PCOS or adult oligomenorrhea was of no value.

    Adolescent AMH either alone or adjuvant to adolescent oligomenorrhea does not contribute as prognostic marker for PCOS in adulthood. Therefore, we do not recommend routine its use in clinical practice.

    Adolescent AMH either alone or adjuvant to adolescent oligomenorrhea does not contribute as prognostic marker for PCOS in adulthood. Therefore, we do not recommend routine its use in clinical practice.

    Wine color is usually considered to be one of the important indicators to judge the red wine quality, and is also employed to evaluate the wine ageing, while the wine color can be influenced by many factors.

    In this paper, the effects of caffeic acid and catechin on the wine color and the mechanism were investigated by high performance liquid chromatography (HPLC) and ultraviolet-visible spectroscopy for the red wine and the constructed model solutions with the addition of catechin, caffeic acid and malvidin-3-O-glucoside, respectively. The spectrum changes of the model wine solutions (Mv-glc, Mv-glc + caffeic acid and Mv-glc + catechin) during the 120 days storage were monitored to analyze the influence of co-pigmentation on the red wine color.

    The results indicate that the color properties of red wine could be affected by caffeic acid and catechin to a certain extent. Moreover, caffeic acid had the stronger auxiliary color effect on the malvidin-3-O-glucoside than that of the catechin in the model wine solutions, and the former effect continued to increase with the prolongation of storage time, while the latter effect (catechin) only had the temporary auxiliary color effect in the beginning, and weakened from red to orange yellow with the increasing of storage time.

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