• 67±2.34) months. All the 11 patients who received corticosteroid injections recovered after 1 to 7 injections, with a median of 3 injections, and an average course of treatment of (2.64±1.69) months. All the 13 patients with oral PPI were cured, with an average course of treatment of (4.15±2.76 )months; No recurrence was found in the follow-up of…[Read more]

  • We identified the fungicide caspofungin as capable of increasing the aqueous solubility of CoQ10 by several orders of magnitude. Caspofungin is a mild surfactant that solubilizes CoQ10 by forming nano-micelles with unique properties favoring stability and cellular uptake. Intravenous administration of the formulation in mice achieves unprecedented…[Read more]

  • The successful licensure of vaccines for biodefense is contingent upon the availability of well-established correlates of protection (CoP) in at least two animal species that can be applied to humans, without the need to assess efficacy in the clinic. Akt inhibitor In this report we describe a multivariate model that combines pre-challenge serum…[Read more]

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