• Since NLRP3 inflammasome plays a pivotal role in several neurodegenerative disorders, we hypothesized that levels of inflammasome components could help in diagnosis or prognosis of amyotrophic lateral sclerosis (ALS). #link# Gene and protein expression was assayed by RT-PCR and Western blot. Spearman’s correlation coefficient was used to determine…[Read more]

  • 055; p = 0.001; R2 = 0.0065) and Attention (β = 4.136; p = 0.002; R2 = 0.0047) domains. No statistically significant associations were observed between quintiles of ARFS and MMSE score in the adjusted linear regression analyses. In conclusion, a positive association was observed between diet quality and cognitive performance within this sample of…[Read more]

  • It is noteworthy that the expression of sma-miR-new_13-3p exhibited a negative correlation on SmNADHubiquinone oxidoreductase complex I.

    Our analysis revealed putative miRNA genes related to important biological processes, such as transforming growth factor beta (TGF-β) signaling, proteasome regulation, glucose and lipid metabolism,…[Read more]

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