Sosa Calderon

Future research should focus on elucidating the oncogenic degree of all EGFR ex20ins variants, the potential role of combination strategies either with chemotherapy or immune checkpoint inhibitors, and the most appropriate first-line treatment strategy in this subgroup. Finally, the knowledge of mechanisms of acquired resistance to these new…[Read more]

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Very good to excellent quality evidence indicated that the SANE scale demonstrates evidence of a reliable, valid and responsive tool in patients with shoulder related pathologies.

PROSPERO CRD42018117874.

PROSPERO CRD42018117874.This paper argues that diverse disciplines within the human sciences have converged in identifying…[Read more]

Split-belt treadmills (SBTM) contain force plates under each belt that measure ground reaction force (GRF). Initial contact (IC) detection for each gait cycle obtained from the GRF is used for calculating temporal gait parameters (e.g., gait variability, step time, stride time). Occasionally, the participant steps with one leg on the contralateral…[Read more]

The cerebellum plays a crucial role in sensorimotor and associative learning. However, the contribution of molecular layer interneurons (MLIs) to these processes is not well understood. We used two-photon microscopy to study the role of ensembles of cerebellar MLIs in a go-no go task where mice obtain a sugar water reward if they lick a spout in…[Read more]

, highlighting opportunities to further care for patients with in-hospital stroke onset.

Preterm and postterm births are associated with adverse neuropsychiatric outcomes. However, it remains unclear whether variation of gestational age within the 37- to 42-week range of term deliveries is associated with neurodevelopment.

To…[Read more]

The mean MCQ scores for all participants improved from 80.3% prior to training to 85.4% following training (P  less then  0.0001) and skills test scores improved from 56.5% to 83.2% (P  less then  0.0001). Improvements in MCQs and skills were maintained at follow-up 3-11 months post-training compared to baseline (P = 0.0006,  less then  0.0001…[Read more]

Caregivers rated anxiety higher than patients before, during and after the procedure (

values <0.001, 0.03, and 0.002, respectively). Providers were less satisfied with the 1- to 2-year age-group compared to the 8+ years age groups (

values 0.01 and 0.002).

Caregiver perception of pain and anxiety of the patient exceeds provider…[Read more]

A survey of dentists and managing clinics-branches of the scientific and practical dental complex showed a high level of professional satisfaction. The main advantages in the activities of rapidly developing network-type dental clinics that actively implement the most advanced, unique technologies and tools have been identified. The main…[Read more]

A survey of dentists and managing clinics-branches of the scientific and practical dental complex showed a high level of professional satisfaction. The main advantages in the activities of rapidly developing network-type dental clinics that actively implement the most advanced, unique technologies and tools have been identified. The main…[Read more]

We present a theoretical approach for calculating the state of stress induced by a uniform magnetic field in confined magnetoactive elastomers of arbitrary shape. The theory explicitly includes the magnetic field generated by magnetizable spherical inclusions in the sample interior assuming a non-linear magnetization behavior. The initial spatial…[Read more]

The enriched pathways included Toll-like receptor (TLR), C-type lectin, NOD-like receptor, and RIG-I-like receptor signaling pathways, etc. Especially, dre-miR-200b-5p, dre-miR-146b, dre-miR-731, dre-miR-222a-3p, and dre-miR-34b were able to target potential immune-related genes such as il10, irak1, traf6, hspa8 and ikbke upon S. parauberis…[Read more]