Jeppesen Gregersen

C3G could spontaneously bind with α-glucosidase to form complexes by hydrogen bonds. The secondary structure of α-glucosidase changed in varying degrees after complexation with C3G. The α-helical and β-turn contents of α-glucosidase decreased, whereas the β-sheet content and the irregular coil structures increased. Molecular docking specu…[Read more]

The facial dermato-muscular system consists of highly specialized muscles tightly adhering to the overlaying skin and thus form a complex morphological conglomerate. This is the anatomical and functional basis for versatile facial expressions, which are essential for human social interaction. The neural innervation of the facial skin and muscles…[Read more]

03, 95% C.I. 0.79 to 1.35), nor increased bleeding (5840/10906 patients, OR 0.84, 95% C.I. 0.65 to 1.08), but it was associated with higher anti-Xa levels (284/294 patients, ES 2.04, 95% C.I. 1.16 to 2.92, p<0.0001). A significant heterogeneity was present for comparison of anti-Xa levels (I

=94%, p=0.0001) but not for VTE occurrence or…[Read more]

481 to 0.798 after calibrated by the resampled measured spectrum model, which effectively enhanced the accuracy in estimating the soil Na+ content at large scale. We successfully made the spatial transformation of soil Na+ content from point to surface. Our results provided a scientific reference for Sentinel-2B image to monitor Na+ content in…[Read more]

The concordance index (C-index) of the nomogram was 0.718, and the areas under the curves (AUCs) of the 3-year and 5-year receiver operating characteristic (ROC) curves were 0.751 and 0.761, respectively. In the external validation set, the C-index was 0.706, and the AUCs of the 3-year and 5-year ROC curves are 0.788 and 0.794,…[Read more]

The General Dental Council (GDC) requires dental practitioners to provide good-quality care based on current evidence and authoritative guidance. SGI-110 However, this leaves the dental practitioner in a sort of limbo as good quality is an ill-defined term allowing its precise meaning to be open to interpretation. This article sets out to…[Read more]

Processive cellulases are highly efficient molecular engines involved in the cellulose breakdown process. However, the mechanism that processive bacterial enzymes utilize to recruit and retain cellulose strands in the catalytic site remains poorly understood. Here, integrated enzymatic assays, protein crystallography and computational approaches…[Read more]