• 5 years, were included. At baseline, 57% received anti-TNFα Etanercept (n = 9), Adalimumab (n = 6), Infliximab (n = 2) and 43% received Rituximab. Good Eular response was obtained in 80% of patients at the third month and 97% of patients at the sixth month. In the analytic study, a significant amelioration after 3 months of biotherapy was found…[Read more]

  • We highlight recent advances in active biomaterials and comment on their future impact.Metal ions imbalance, a well-established pathologic feature of alzheimer’s disease (AD), ultimately results in the deposition of amyloid-β peptide (Aβ) proteins and Aβ-induced neurotoxicity. Herein, to overcome these hurdles, an intelligent Aβ nanocaptor wit…[Read more]

  • he accuracy of meta-analyses performed for studies analysing time-to-event outcomes. The nlopt source code is available, as is a simple-to-use web implementation of the method.

    Classification of diseases based on genetic information is of great significance as the basis for precision medicine, increasing the understanding of disease etiology…[Read more]

  • To report on the application of the 3D exoscopic system to microsurgery in a cohort of head and neck cancer patients; to analyse the performance of microvascular anastomoses, flap harvesting and insetting under exoscopic view and to evaluate the surgeon’s feedback after procedures.

    An observational study was performed on 10 consecutive…[Read more]

  • Background While there is growing awareness of the need to support the physical and mental wellbeing of transgender people, some may be reluctant to seek help from healthcare professionals. Little is understood about the mechanisms that influence help-seeking behavior in this group. Aims This study aimed to compare transgender and cisgender…[Read more]

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