• Hvid Hyde posted an update 6 months, 3 weeks ago

    The aim of the present study was to understand the biology of unintegrated HIV-1 DNA and reveal the mechanisms involved in its transcriptional silencing. We found that histones are loaded on HIV-1 DNA after its nuclear import and before its integration in the host genome. Nucleosome positioning analysis along the unintegrated and integrated viral…[Read more]

  • Hvid Hyde posted an update 6 months, 3 weeks ago

    The Kalman filter provides a simple and efficient algorithm to compute the posterior distribution for state-space models where both the latent state and measurement models are linear and gaussian. Extensions to the Kalman filter, including the extended and unscented Kalman filters, incorporate linearizations for models where the observation model…[Read more]

  • Hvid Hyde became a registered member 6 months, 3 weeks ago