Dreier McCracken

Nevertheless, our investigation revealed that variations in the BCL2L1 copy number (CNVs) do not accurately forecast BCL-XL expression levels, although the BCL-XL protein concentration serves as a valuable indicator for anticipating GC cell susceptibility to BCL-XL-targeted compounds. Through our study, BCL-XL emerged as a promising drug target…[Read more]

A study into the clinical presentation of SF3B1-mutated myelodysplastic syndrome with excess blasts (MDS-EB) was undertaken, with a focus on establishing the relationship between the presence of an SF3B1 mutation and therapeutic success and prognostic factors for patients with MDS-EB. This investigation utilized a retrospective case series study…[Read more]

In order to investigate five body size traits, a genome-wide association study (GWAS) was performed on 31 yak breeds and genetic resources. The compressed mixed linear model (CMLM) employed habitat-based individual clustering to ascertain kinship groupings. We have coined the term pCMLM method for this approach. Following pCMLM analysis of…[Read more]