Blum Austin

Our findings thus provide fundamental information to help understand the molecular mechanism of bacterial protection offered by insect-derived immunostimulatory polysaccharides in teleosts.A diverse medical workforce is pivotal for the provision of high-quality healthcare services to the US population.1 Currently, women comprise 50% of all medical…[Read more]

Downregulated genes (N = 363) were enriched in annotations associated with behavior (FDR less then 2 × 10-4 ), membrane organization (FDR less then 1 × 10-4 ), inorganic cation transmembrane transporter activity (FDR less then 2 × 10-3 ), synapse part (FDR less then 4 × 10-10 ), glutamatergic synapse (FDR less then 1 × 10-6 ), and GABAergic syna…[Read more]

The significance level for all tests was 5%.

TXNIP protein expression was higher and Trx activity was lower in VD10. The animals supplemented with VD showed increased lipid hydroperoxide and decreased superoxide dismutase and glutathione peroxidase. The protein Bcl-2 was lower in VD10. There was a decrease in fatty acid β-oxidation,…[Read more]

Bacterial resistance to antibiotics makes previously manageable infections again disabling and lethal, highlighting the need for new antibacterial strategies. In this regard, inhibition of the bacterial division process by targeting key protein FtsZ has been recognized as an attractive approach for discovering new antibiotics. Binding of small…[Read more]

Massive hemorrhage caused by the uncontrolled release of thrombolysis drugs is a key issue of thrombolysis therapy in clinical practice. In this study, we report a near-infrared (NIR) light-triggered drug delivery system, i.e., CuS@mSiO2-PEG (CSP) nanoparticles, for the loading of a thrombolytic drug (urokinase plasminogen activators, uPA). CSP…[Read more]

In vivo experiments further confirmed the pro-tumor effect of IL-33 on NSCLC. The study on the underlying mechanism elucidated that IL-33 regulates the expression of miR-128-3p, which can directly target and inhibit the expression of CDIP1. find more Furthermore, IL-33 regulates the expression of downstream apoptotic proteins such as bax, cyt-c,…[Read more]