Konradsen Mccormick

OBJECTIVE Lipocalin-type prostaglandin D synthase (L-PGDS) catalyzes the formation of prostaglandin D2 (PGD2), which has important roles in inflammation and cartilage metabolism. The aim of this study was to investigate the role of L-PGDS in the pathogenesis of OA using an experimental mouse model. METHODS Experimental OA was induced in wild-type…[Read more]

OBJECTIVE Lipocalin-type prostaglandin D synthase (L-PGDS) catalyzes the formation of prostaglandin D2 (PGD2), which has important roles in inflammation and cartilage metabolism. The aim of this study was to investigate the role of L-PGDS in the pathogenesis of OA using an experimental mouse model. METHODS Experimental OA was induced in wild-type…[Read more]

Iron is an essential component for growth and development. Despite relative abundance in the environment, bioavailability of iron is limited due to oxidation by atmospheric oxygen into insoluble ferric iron. Filamentous fungi have developed diverse pathways to uptake and use iron. In the current study, a putative iron utilization gene cluster…[Read more]

In order to explore the angular strain role on the ability of Be to form strong beryllium bonds, a theoretical study of the complexes of four beryllium derivatives of orthocloso-carboranes with eight molecules (CO, N2, NCH, CNH, OH2, SH2, NH3, and PH3) acting as Lewis bases has been carried out at the G4 computational level. The results for these…[Read more]

Reversal learning, a component of executive functioning, is commonly impaired among schizophrenia patients and is lacking effective treatment. N-methyl-ᴅ-aspartate (NMDA) receptor antagonists, such as phencyclidine (PCP), impair reversal learning of rodents. Touchscreen-based pairwise visual discrimination and reversal test is a translational t…[Read more]

d could have adversely affected chances of maintaining MCID, most patients did not have failure at long-term follow-up.The unified construction of cyano-substituted 1,2,4-triazoles, particularly the 5-cyano counterparts, remains underdeveloped. Herein we describe a three-component method to access a wide range of 1-aryl 5-cyano-1,2,4-triazoles…[Read more]

Meanwhile, molecules with ortho-position substitutions possess the smallest energy gaps (ΔEst) and the largest RISC rates. Moreover, molecules with the substitutions of one tBCz group and two PO groups have the smallest ΔEst and the largest spin orbital coupling. Thus, a wise molecular design strategy, namely, ortho-position substitutions as w…[Read more]

Furthermore, she received radiation therapy for left parasternal lymph node metastasis 6months later. The patient recovered well. Consequently, she has no evidence of disease > 15years after pancreatectomy.

This is the first reported case of pancreatectomy for pancreatic metastases from breast cancer, which was simultaneously dia…[Read more]

Furthermore, she received radiation therapy for left parasternal lymph node metastasis 6months later. The patient recovered well. Consequently, she has no evidence of disease > 15years after pancreatectomy.

This is the first reported case of pancreatectomy for pancreatic metastases from breast cancer, which was simultaneously dia…[Read more]

Figures of merit for comparing semiconductor materials and devices are also presented in this review.Neuromuscular diseases (NMDs) belong to a class of functional impairments that cause dysfunctions of the motor neuron-muscle functional axis components. Inherited monogenic neuromuscular disorders encompass both muscular dystrophies and motor…[Read more]