McPherson McFadden

All cases of iT-LBP were negative for LMO2 (0/7) while 92% of T-LBL cases (12/13) expressed LMO2; sensitivity 92% (confidence interval 64-100%) and specificity 100% (confidence interval 59-100%). Conclusion We confirm prior published findings that cases of iT-LBPs demonstrate highly overlapping morphologic and immunophenotypic features when…[Read more]

Objective Long-acting injectable (LAI) antipsychotics, such as paliperidone palmitate (PP), are known to improve treatment adherence in patients with schizophrenia, which can lead to reductions in relapse and hospitalization rates. However, relatively few studies have demonstrated the economic impact of LAIs, especially in Asian populations.…[Read more]

The authors emphasize the anatomical correlations of PTSD’s hallmark symptoms, offer another potential deep brain stimulation target for PTSD, and note the need for continued research to identify useful biomarkers for the development of closed-loop therapies. Although there is hope that neuromodulation will become a viable treatment modality for…[Read more]

Reducing the amount of vertical reinforcement lowered the resulting shear strength, although it also slowed down the post-peak resistance degradation. Transversal edge elements provided integrity to the wall response, generated softer resistance degradation, and improved the symmetry of the response, but they did not raise the lateral…[Read more]

On average, 94.5% of the photographs were deemed to have visible optic discs and 50.0% to have visible maculae adequate for detecting an abnormality. Pairwise comparison showed 93.7% agreement among the four professionals for optic disc visibility, and 74.2% agreement for macula visibility. CONCLUSION The oDocs Nun is a promising tool which GPs…[Read more]

Regarding the latter, prominence is laid upon inherited susceptibility genes and the genetic and epigenetic abnormalities that lead to the developmental and progression of the disease. Copyright © 2020 Cold Spring Harbor Laboratory Press; all rights reserved.Many exposures considered in Mendelian randomization (MR) studies are polygenic in that…[Read more]