• The androgen receptor (AR) has been found to be expressed in the majority of human breast cancer and AR antagonists, such as enzalutamide, have shown promising clinical activity in AR-positive (AR+) breast cancer. Molibresib nmr We have recently reported the discovery of a highly potent PROTAC AR degrader, ARD-61. In this study, we evaluated…[Read more]

  • Objective To investigate the effect of stomatin protein expression on the proliferation and apoptosis of lung cancer cells. Methods The expressions of stomatin mRNA in human bronchial epithelial cells (HBE) and lung cancer cells (H520, A549, 95D, H460, Glc-82, 973 and H1299) were detected by Real-time PCR. Immunohistochemistry (IHC) was used to…[Read more]

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