Petersson Garcia

s exhibited polyfunctional effector responses to two novel NC-derived peptides identified as HLA-binders. These studies provide a proof of concept that our immunoinformatics analysis pipeline identifies novel immunogens which can elicit polyfunctional SARS-CoV-2-specific T-cell responses.Idiopathic pulmonary fibrosis (IPF) is characterized by…[Read more]

The model predicted that the KSQ mAb can be dosed over a less frequent regimen or at lower dose levels than the current monalizumab clinical dosing regimen of 10 mg/kg q2w. Either dosing strategy represents a competitive advantage over the current therapy. The results of this study demonstrate a key role for mechanistic modeling in identifying…[Read more]

25% and 93.75% of accuracy in the first level and second level of classification, respectively. Lastly, a comparative performance analysis is carried out with several other previously published works on a similar dataset where the proposed approach performs better than its contemporary methods.The objective of this study was to use high-energy…[Read more]

25% and 93.75% of accuracy in the first level and second level of classification, respectively. Lastly, a comparative performance analysis is carried out with several other previously published works on a similar dataset where the proposed approach performs better than its contemporary methods.The objective of this study was to use high-energy…[Read more]

78 ~ 7.53 mg/g, OR = 1.21, 95% confidence interval 1.05-1.40) and the third quartile in females (UACR 9.13 ~ 15.04 mg/g, OR = 3.07, 95% CI 1.75-5.40). Stratified analysis showed that in males, the association was especially pronounced in elderly, overweight/obese participants and those without diabetes and hypertension whereas in females, th…[Read more]

Cardiovascular disease and the metabolic syndrome are major contributors to health care expenditure. Increased physical activity reduces disease risk. The study compared effects of walking up and down stairs at home with continuous, gym-based stair climbing on the disease risk factors of aerobic fitness, serum lipids, body composition, fasting…[Read more]