Clemensen Bass

Mutations at sites crucial for the interaction between RAD51 and BRC domains impair the ability of BRCA2 homologous recombination. We aimed to clarify whether BRCA2 BRC domain-associated mutation correlates with sensibility of platinum-based chemotherapy and survival in high-grade serous ovarian cancer (HGSOC).

We identified BRCA2 BRC…[Read more]

Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Crenigacestat Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).We developed prognostic models for breast cancer-specific survival (BCSS) that…[Read more]

Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Crenigacestat Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).We developed prognostic models for breast cancer-specific survival (BCSS) that…[Read more]

The BCSCs were found to have characteristics of CD44+/CD24-/low epithelial surface antigen (ESA) and ALDH+ with flow cytometry. The phage was enriched to 200-fold after three rounds of screening for MDA-MB-231 BCSCs. The positive phages were sequenced; then a polypeptide named M58 was synthesized according to sequencing results. Polypeptide M58…[Read more]

The BCSCs were found to have characteristics of CD44+/CD24-/low epithelial surface antigen (ESA) and ALDH+ with flow cytometry. The phage was enriched to 200-fold after three rounds of screening for MDA-MB-231 BCSCs. The positive phages were sequenced; then a polypeptide named M58 was synthesized according to sequencing results. Polypeptide M58…[Read more]

The study explores the antioxidant activity, volatile chemical profile and antifungal potential of Pimenta dioica leaf essential oil (EO) against toxin producing Aspergillus flavus. GC-MS analysis of EO revealed the presence of 41 compounds with eugenol (54%), as the major compound followed by myrcene (16.0%) and chavicol (12.5%). It exhibited the…[Read more]

The method presented here shall be used for analysis of urine samples collected in the upcoming German Environmental Survey, GerES VI, a cross-sectional, population-representative study.A facile pyrolysis-quenching-reroasting process was developed to prepare a sludge-based biochar adsorbent, and its adsorption performance for Cr(VI) ions was…[Read more]

The method presented here shall be used for analysis of urine samples collected in the upcoming German Environmental Survey, GerES VI, a cross-sectional, population-representative study.A facile pyrolysis-quenching-reroasting process was developed to prepare a sludge-based biochar adsorbent, and its adsorption performance for Cr(VI) ions was…[Read more]

Immobilizing metal atoms by multiple nitrogen atoms has triggered exceptional catalytic activity toward many critical electrochemical reactions due to their merits of highly unsaturated coordination and strong metal-substrate interaction. Herein, atomically dispersed Fe-NC material with precise sulfur modification to Fe periphery (termed as…[Read more]