Dominguez Vogel

A unique lanthanide complex which responds to near-infrared (NIR) stimulation was developed for remote regulation of cellular events. This molecule can be localized specifically on the cell surface. Upon NIR stimulation, strong emission of the complex can successfully modulate the activities of light-gated membrane channels and regulate the ion…[Read more]

The current COVID-19 outbreak warrants the design and development of novel anti-COVID therapeutics. Using a combination of bioinformatics and computational tools, we modelled the 3D structure of the RdRp (RNA-dependent RNA polymerase) of SARS-CoV2 (severe acute respiratory syndrome coronavirus-2) and predicted its probable GTP binding pocket in…[Read more]

The regression analysis indicated a higher risk of distress with increasing age and greater negative religious coping.

In this sample, higher means were found in the dimension of positive distress experiences; negative coping, although utilized less, had greater potential to exacerbate distress after adjustment for age, in contrast to that…[Read more]

Over the past decades, professional medical authority has been transformed due to internal and external pressures, including weakened institutional support and patient-centered care. Today’s patients are more likely to resist treatment recommendations. We examine how patient resistance to treatment recommendations indexes the strength of…[Read more]

Current therapies in Alzheimer’s disease (AD), including Memantine, have proven to be only symptomatic but not curative or disease modifying. Fluoroethylnormemantine (FENM) is a structural analogue of Memantine, functionalized with a fluorine group that allowed its use as a positron emission tomography tracer. We here analyzed FENM neuroprotective…[Read more]

dementia. Future research is needed to confirm the substantial mortality burden of heat and cold.Focusing attention on a movement effect that is farther away from the body (distal external focus) has been shown to result in more effective motor performance or learning than focusing on an effect that is in greater proximity to the body (proximal…[Read more]