Thrane McKay

Sphingosine 1-phosphate receptor 1 (S1PR1) plays a pivotal role in mediating trafficking and migration of immune cells. Previous reports also identify S1PR1 as an important susceptibility gene of asthma and other autoimmune disorders. However, little has been known about the regulatory mechanism of S1PR1 expression. Thus we systematically…[Read more]

s conclusion was low. For second-generation quinolones and co-trimoxazole, single-dose regimen was less effective than 3-day regimen in clinical response, with moderate quality of evidence. Interpretation Treatment duration of the third-generation and fourth-generation quinolones and pivmecillinam could be shorter than the currently recommended…[Read more]

Purpose We report the clinical courses of two patients with papillomacular retinoschisis in eyes with advanced glaucomatous optic neuropathy. Observations In case 1, a 67-year-old woman was diagnosed with papillomacular retinoschisis and normal tension glaucoma in the left eye. Her medication was switched from topical latanoprost to brinzolamide,…[Read more]

Background Up to 33% of women report a negative or traumatic childbirth experience. Given this high prevalence and its consistent association with adverse postpartum and child outcomes, it is essential to identify predictive factors and to improve the management of the childbirth experience. Objective This systematic review explores and identifies…[Read more]

61, 95% CI 13.37-79.54, p less then 0.001) and open surgery (OR 6.78, 95% CI 2.18-21.03, p=0.001). NP incidence was higher in female patients (16% in women and 6% in men respectively, p=0.040). A significant decrease in all SF-36 Health Survey domains scores was recorded for CPSP patients and patients with NP (p less then 0.001). CONCLUSION Over 1…[Read more]