• Reddy Espersen posted an update 6 months ago

    Here, we conduct a comprehensive review and discussion of the bibliography available regarding the role of polyP in the mitochondrial dysfunction present in AD and PD. Taking into account the data presented in this review, we postulate that polyP could be a valid, innovative and, plausible pharmacological target against mitochondrial dysfunction…[Read more]

  • Reddy Espersen posted an update 6 months ago

    In this work, we extensively review the current literature focusing on studies that used state-of-the-art techniques to interrogate the neuroanatomy, connectomics, neurotransmitter-receptor functions, and sex-derived differences in the PPI process, and how we can harness it as biological marker in neurological and psychiatric…[Read more]

  • Reddy Espersen posted an update 6 months ago

    These results exhibit different hydration environments for the causative and protective mutants highlighting the differential roles of charge and hydrophobicity.Curcumin, a molecule of labile natural product, has multiplex pharmacological effects, including antioxidant, antimicrobial, and anticancer effects as well as anti-Alzheimer’s disease (AD)…[Read more]

  • Reddy Espersen posted an update 6 months ago

    These results exhibit different hydration environments for the causative and protective mutants highlighting the differential roles of charge and hydrophobicity.Curcumin, a molecule of labile natural product, has multiplex pharmacological effects, including antioxidant, antimicrobial, and anticancer effects as well as anti-Alzheimer’s disease (AD)…[Read more]

  • Reddy Espersen posted an update 6 months ago

    These results exhibit different hydration environments for the causative and protective mutants highlighting the differential roles of charge and hydrophobicity.Curcumin, a molecule of labile natural product, has multiplex pharmacological effects, including antioxidant, antimicrobial, and anticancer effects as well as anti-Alzheimer’s disease (AD)…[Read more]

  • Reddy Espersen posted an update 6 months ago

    3±1.0). They agreed that the models would be useful teaching tools for both medical learners (x̅=4.8±0.5) and patients (x̅=4.8±0.7). Following an educational session with the models, medical learners reported improvements in confidence and skill in performing a testicular examination.

    3D-printed models can effectively simulate palp…[Read more]

  • Reddy Espersen posted an update 6 months ago

    The paper presents the influence of the milling strategy, the relation between the cutting tool feed direction and the rolling direction, as well as the pre-machining consisting of the removal of the textured surface layer of rolled plates in the rolling process on the thin-walled elements deformations made of the EN AW-2024 T351 wrought aluminium…[Read more]

  • 05; 5h p<0.01) and a standard high fibre bread (5h p<0.05). Concurrently, significant increases in plasma FA levels were observed, at 2h (p<0.01) after consumption of the enzyme-treated bread, relative to control treatments. Blood pressure, heart rate, DVP-SI and DVP-RI were not significantly altered following intake of any of the breads…[Read more]

  • Reddy Espersen became a registered member 6 months, 1 week ago