• Human prion diseases are etiologically categorized into three forms sporadic, genetic, and infectious. Sporadic Creutzfeldt-Jakob disease (sCJD) is the most common type of human prion disease that manifests as subacute progressive dementia. No effective therapy for sCJD is currently available. Potential therapeutic compounds are frequently tested…[Read more]

  • In summary, we uncovered MAT2A as a key regulator in MLL leukemogenesis and its inhibition led to significant anti-leukemic effects. Therefore, our study paves the avenue for clinical application of PF-9366 to improve the treatment of poor prognosis MLLr leukemia.Background Classification of colorectal neoplasms during colonoscopic examination is…[Read more]

  • Stout Bain became a registered member 6 months, 3 weeks ago