Vognsen Roche

elected older patients represent a significant larger proportion in real life than in RCTs; furthermore, older patients in a real-world setting may experience more side effects possibly affecting the quality of life. The median PFS data suggest that older patients may not derive the same clinical benefit than their fit and younger…[Read more]

Patients undergoing haemodialysis (HD) are often discouraged from eating fruits and vegetables because of fears of hyperkalaemia and undernutrition, yet evidence to support these claims is scarce. We here explore the association between adherence to a healthy plant-based diet with serum potassium, surrogates of nutritional status and attainment of…[Read more]

For those patients with valvular heart disease, cardiomyopathy, or hypertension, it is reasonable to initiate a progestin-only method until clarification of the safety of an estrogen-containing method is determined in conjunction with the patient’s cardiologist. Contraceptive counseling should be patient-centered, free of coercion, and should…[Read more]

The survey looked at 14 areas of care across five stages of the patient journey. Of the non-extracting physicians over 50% felt they lacked the knowledge and skills to make the diagnosis and refer for lead extraction and over 75% felt they lacked knowledge and skills to manage aspects of extraction and post-extraction care. Barriers to correct…[Read more]

Patients underwent a significant change in lumbar alignment (Δpelvic incidence-lumbar lordosis mismatch 21° ± 16°, P < 0.001); 35.0% had UIV in the upper thoracic region, and 65.0% had UIV in the lower thoracic region. At 1 year, revision rate was 11.9%, and rate of radiographic proximal junctional kyphosis was 29.4%. Neural network comprised 8 i…[Read more]

The modern approach to sepsis has focused on creating a global consensus with different criteria to early investigate it in order to reduce the morbidity and mortality associated with this complex entity. Until the third and last consensus of adults (Sepsis-3), the systemic inflammatory response syndrome (SIRS) was the diagnostic pillar used by…[Read more]

Both compounds were effective (though O23 was the more effective) at ameliorating extrapyramidal and non-motor symptoms in the model and improved locomotory and exploratory behaviors, reduced oxidative stress markers, and enhanced antioxidant marker and neurotransmitter levels. Furthermore, histopathological studies showed O10 and O23 both reduced…[Read more]

The XMT-SSSA values deviated from the GSSA values by 7-16% for the first four experiments, but were essentially identical for the later experiments. This indicates that enhancements in image acquisition and processing improved data accuracy. The Amax values ranged from 74 cm-1 to 101 cm-1, with a coefficient of variation (COV) of 9%. The maximum…[Read more]

The XMT-SSSA values deviated from the GSSA values by 7-16% for the first four experiments, but were essentially identical for the later experiments. This indicates that enhancements in image acquisition and processing improved data accuracy. The Amax values ranged from 74 cm-1 to 101 cm-1, with a coefficient of variation (COV) of 9%. The maximum…[Read more]

The XMT-SSSA values deviated from the GSSA values by 7-16% for the first four experiments, but were essentially identical for the later experiments. This indicates that enhancements in image acquisition and processing improved data accuracy. The Amax values ranged from 74 cm-1 to 101 cm-1, with a coefficient of variation (COV) of 9%. The maximum…[Read more]

18–12.83];

= 0.002). Mean urine output (-112.68 ,

= 0.17), incidence of AKI (RR = 1.05 ,

= 0.72), and mortality rates (RR = 0.79 ,

= 0.45) were found to be statistically insignificant.

Aminophylline administration in children with AKI reduces serum creatinine level without significant adverse effects or effect on the…[Read more]