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Suhr Tobiasen posted an update 6 months, 4 weeks ago
3%) were categorized as grade Ⅰ and 21 (56.7%) as grade Ⅱ, and so the affected testes were preserved in all the cases during the operation. The patients were followed up for 12 months postoperatively, which revealed testicular atrophy in 6 cases (16.2%). CONCLUSIONS ITT occurs in children at a young age, of less than 360 degrees in all cases, mostly 180 degrees, and the survival rate of the affected testis is high after surgery. Reduction in testicular blood flow signals at preoperative color Doppler examination is an important indication in the diagnosis of the disease.Objective To investigate the efficacy and safety of lycopene in the treatment of BPH with lower urinary tract symptoms (LUTS). METHODS Totally, 127 BPH patients with LUTS were treated with oral lycopene tablets at 500 mg bid in the Department of Andrology of Jinling Hospital from January 2018 to January 2019. At 8 and 16 weeks of medication, we compared the IPSS, quality of life (QOL) score, prostate volume, PSA level, maximum urinary flow rate (Qmax), postvoid residual urine volume (PVR) and the incidence of adverse reactions before and after treatment. RESULTS A total of 120 patients completed the treatment. Compared with the baseline, significant improvement was observed after 8 weeks of medication in the IPSS ([18.42 ± 4.59] vs [14.13 ± 4.51], P 0.05), and no adverse reactions in any of the patients. CONCLUSIONS Lycopene has a good therapeutic effect on BPH with LUTS, which can significantly improve the patients’ quality of life without causing adverse reactions.Objective To investigate the personality and psychological characteristics of premature ejaculation (PE) patients and the correlation between them two. METHODS Using Eysenck Personality Questionnaire (EPQ) and Symptom Checklist 90 (SCL-90), we conducted an investigation among 94 PE patients seeking medical advice in Drum Tower Hospital from October 2018 to February 2019. RESULTS The neuroticism score of the PE patients on EPQ was significantly higher than the national norm of adult males (t = 12.010, P less then 0.01), and so was their introversion-extroversion score (t = 2.557, P less then 0.05), while their concealment score was markedly lower (t = -8.736, P less then 0.01). The coercion score of the patients on SCL-90 was remarkably higher than the national norm of adult males (t = 2.787, P less then 0.01), and so were their psychosis score (t = 3.944, P less then 0.01) and anxiety score (t = 2.512, P less then 0.05). There was a significant correlation between the EPQ and SCL-90 scores of the less then 0.05) and depression (r = -0.228, P less then 0.05), and so was concealment with terror (r= - 0.351, P less then 0.01), interpersonal relationship (r = -0.433, P less then 0.01), hostility (r = -0.347, P less then 0.01), psychosis (r = -0.427, P less then 0.01), compulsion (r = -0.345, P less then 0.01), depression (r = -0.379, P less then 0.01) , paranoia (r = -0.393, P less then 0.01), somatization (r = -0.204, P less then 0.05) and anxiety (r =-0.237, P less then 0.05). CONCLUSIONS The personality and psychological status of PE patients are different from those of normal males, and some personality characteristics of the patients are correlated with their psychological status, especially with high neuroticism.Objective To explore the application value of elastic ultrasound (EUS) and contrast-enhanced ultrasonography (CEUS) in detecting the changes of testicular blood supply after blockage of the vas deferens artery. METHODS This study included 11 cases of microscopic varicocele ligation. We obtained the EUS and CEUS values of the patients before and after blocking the vas deferens artery and analyzed the data by paired comparison. RESULTS After the blockage of the vas deferens artery, the testicular hardness was reduced across the tunica albuginea and within the testis, with Ave decreased from 11.44 ± 2.52 before to 6.21 ± 1.16 after the blockage of the vas deferens artery across the tunica albuginea (P 0.05). CONCLUSIONS Elastic ultrasound and contrast-enhanced ultrasonography play important roles in evaluating the changes of testicular blood supply in different states.Objective To study the relationship between semen quality and the methylation level of maternally expressed gene 3 (MEG3) in sperm. METHODS We collected the general demographic data, semen samples and results of clinical semen analysis from 403 married men undergoing pre-conception examinations in March and April 2015 and March and April 2016. Using pyrosequencing, we quantitatively detected the methylation level at 8 CpG sites in the differentially methylated region of MEG3, and subjected the data obtained to variance analysis, Pearson correlation analysis, two-sample t-test and multivariate linear regression analysis. RESULTS Both the individual and mean methylation levels at CpG sites 1-8 of MEG3 were correlated highly negatively with sperm concentration (P 0.05). The men with an abnormal sperm concentration exhibited significantly higher individual and mean methylation levels at the 8 CpG sites than those with a normal one (P less then 0.05). After adjusting for age as a confounding factor, multivariate linear regression analysis showed a decrease of 1.684 × 106/mL in sperm concentration for every 1% increase in the average methylation of MEG3 (P less then 0.05). CONCLUSIONS The imprinting gene MEG3 is involved in spermatogenesis and its methylation level may influence sperm concentration.Objective To investigate the expression of the sperm-specific cation channel (CatSper1) in the epididymal sperm of varicocele (VC) rats and the effect of L-carnitine (LC) on the CatSper1 level. METHODS Seventy male rats were equally randomized into groups A (normal control), B (VC model control), C (VC treated with normal saline), D (VC treated with low-dose LC), E (VC treated with medium-dose LC), F (VC treated with high-dose LC), and G (VC treated by prolonged medication of high-dose LC). The VC model was established by partial ligation of the left renal vein. At 12 weeks after modeling, the model rats in group C were treated intragastrically with normal saline at 1 ml/kg/d, those in groups D, E and F with LC at 0.05, 0.1 and 0.2 g/kg/d respectively, all for 5 consecutive weeks, and those in group G with LC at 0.2 g/kg/d for 7 successive weeks. see more Then, all the animals were sacrificed and their epididymides harvested for obtainment of the semen parameters by computer-assisted semen analysis (CASA) and determination of the mRNA and protein expressions of CatSper1 in the sperm by RT-PCR and Western blot.