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Friedman Lee posted an update 6 months, 2 weeks ago
(iv) Data from pediatric population are too scarce to draw any conclusions. (v) Differences in laboratory protocols and in criteria used in the assessment of ELISpot plates along with the issue of the technical feasibility and reproducibility may limit the use of this assay in the routine diagnostic of drug hypersensitivity reactions.
To characterize the types of multisite pain experienced by children with functional abdominal pain disorders (FAPDs) and to examine differences in psychosocial distress, functional disability, and health-related quality of life in children with multisite pain vs abdominal pain alone.
Cross-sectional study of children ages 7-17years (n=406) with pediatric Rome III FAPDs recruited from both primary and tertiary care between January 2009 and June 2018. Subjects completed 14-day pain and stool diaries, as well as validated questionnaires assessing abdominal and nonabdominal pain symptoms, anxiety, depression, functional disability, and health-related quality of life.
In total, 295 (73%) children endorsed at least 1 co-occurring nonabdominal pain, thus, were categorized as having multisite pain with the following symptoms 172 (42%) headaches, 143 (35%) chest pain, 134 (33%) muscle soreness, 110 (27%) back pain, 94 (23%) joint pain, and 87 (21%) extremity (arms and legs) pain. In addition, 200 children (49%)
To assess the first attempt neonatal intubation success rates of pediatric trainees following the implementation of an evidence-based training package.
Data collection was undertaken from February, 1 2017, to January 31, 2018, to ascertain baseline preimplementation intubation success rates. An intubation training package, which included the use of videolaryngoscopy, preprocedure pause, and standardized instruction during the procedure, was introduced. https://www.selleckchem.com/products/bmn-673.html Data on all subsequent intubations were collected prospectively from May 1, 2018, to April 30,2020.
Preimplementation baseline data over a 1-year period demonstrated overall first attempt intubation success rate of junior trainees to be 37% (33/89). After implementation of the training package, 290 intubations were analyzed over a 2-year period. The overall success rate was 67% (194/290); 61% (117/192) for junior trainees and 79% (77/98) for senior clinicians. Three or more attempts were required for 13% of intubations (38/290). During the study period, the overall number of intubations being carried out decreased. Intubations with the videolaryngoscope had higher success rates for all tiers of clinician, most marked in the junior tiers.
The introduction of a standardized intubation training package, along with videolaryngoscopy, improved trainee intubation success rates.
The introduction of a standardized intubation training package, along with videolaryngoscopy, improved trainee intubation success rates.
To test the hypothesis that newborn infants cared for in hospitals with greater utilization of neonatal intensive care experienced fewer postdischarge adverse events.
We developed 3 retrospective population-based cohorts of Texas Medicaid insured singletons born in 2010-2014 (very low birth weight , late preterm , and non-preterm ) who received care in higher volume hospitals with level III/IV neonatal intensive care units (NICUs). Measures of NICU care were hospital-level risk adjusted NICU admission rates, special care days (days of nonroutine care) per infant, and the percent of intensive (highest billable care code) special care days. The units of analysis were hospitals (n=80) and the primary outcome was an adverse event, (defined as admission, emergency department visit, or death) within 30days postdischarge.
Higher use of NICU care at a hospital level was not associated with lower postdischarge 30-day adverse event. Infants cared for in hospitals with above vs below median special care day rates experienced slightly higher postdischarge adverse event per 100 infants (VLBW 14.01 vs 11.84 , P<.05; late preterm 7.33 vs 6.28 , P<.01; non-preterm 4.47 vs 3.97 , P<.01). Weak positive associations (Pearson correlations of 0.31-0.37, P<.01) were observed for adverse event with special care days; in no instance was a negative association observed between NICU utilization and adverse event.
Higher utilization of NICU care was not associated with lower rates of short-term events suggesting that there may be opportunities to safely decrease admission rates and length of NICU stays.
Higher utilization of NICU care was not associated with lower rates of short-term events suggesting that there may be opportunities to safely decrease admission rates and length of NICU stays.
To investigate variation by parental incarceration history in the bedtime schedules set for elementary-age children and whether sleep was effectively regulated.
We ran multivariate regression models estimating the relationship between parental incarceration and six measures of bedtime schedules and sleep regulation. Our sample included 9-year-olds in the Fragile Families and Child Wellbeing Study (N=3246), a survey of children born in large U.S. cities between 1998 and 2000 that has an oversample of unmarried mothers.
Children’s bedtime schedules did not differ at a statistically significant level by parental incarceration history, but children of ever- versus never-incarcerated fathers had lower odds of consistently adhering to a set bedtime. Children of ever-incarcerated fathers also slept for less time on average than did children of never-incarcerated fathers, and they had lower odds of obtaining sufficient sleep. Bedtime consistency partly mediated the association between paternal incarceration and total sleep duration.
Although caregivers set appropriate bedtime schedules for children of ever-incarcerated fathers, consistent adherence to those schedules may be particularly challenging given the structural hardships of paternal incarceration. Policymakers, researchers, and practitioners working to improve sleep among children of incarcerated fathers should focus on helping families develop strategies for implementing bedtime schedules as consistently and effectively as possible.
Although caregivers set appropriate bedtime schedules for children of ever-incarcerated fathers, consistent adherence to those schedules may be particularly challenging given the structural hardships of paternal incarceration. Policymakers, researchers, and practitioners working to improve sleep among children of incarcerated fathers should focus on helping families develop strategies for implementing bedtime schedules as consistently and effectively as possible.