• 3%, -0.8%, and 0.7% for shape geometry and -0.8%, 14.1%, and 0.7% for toolmark geometry for Printers 1-3 respectively). Where possible, the authors recommend micro-CT imaging for producing forensic 3D printed bone models particularly when injuries are present.The Joint Casualty and Compassionate Centre Commemorations team (JCCC), part of the…[Read more]

  • our understanding of this complex disease.

    The identification of acute injury of the kidney relies on serum creatinine (SCr), a functional marker with poor temporal resolution as well as limited sensitivity and specificity for cellular injury. In contrast, urinary biomarkers of kidney injury have the potential to detect cellular stress and…[Read more]

  • The association between protein aggregation and neurodegenerative diseases such as Parkinson’s disease continues to be well interrogated but poorly elucidated at a mechanistic level. Nevertheless, the formation of amyloid fibrils from the destabilization and misfolding of native proteins is a molecular hallmark of disease. TPH104m solubility dmso[Read more]

  • Tacrolimus, which bonds to an immunophilin, FK506 binding protein (FKBP) has emerged as one of the most widely used immunosuppressant post solid organ transplantation. It offers excellent patient survival rates post-transplantation and a lesser number of acute rejections as compared to cyclosporine. find more Tacrolimus has a narrow therapeutic…[Read more]

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