Tuttle Leblanc

Conclusions A lag time close to 0 second was associated with higher FI, representing hyperefficient voiding with a tower-shaped flow pattern. However, children with prolonged or delayed lag time showed a lower FI, implicating hypoefficient voiding and a plateau-shaped flow pattern. The relationship between FI and EMG lag time could be a…[Read more]

This study discloses some structural features for binding to 15-LOX and COX, thus pave the way to design anti-inflammatory agents with balanced dual inhibition of these enzymes. Inhibitors of aldose reductase are rate-limiting enzymes and could play a key role to prevent the complications of diabetes. In our attempt to develop novel inhibitors of…[Read more]

Purpose To characterize ocular perfusion pressure (OPP) fluctuations with continuous telemetry over 24-hour periods across multiple days in nonhuman primates (NHPs) to test the hypotheses that OPP differs among NHPs and that the diurnal cycle of OPP is characterized by low OPP during sleep. Methods We have developed and validated two implantable…[Read more]

We describe a case of ectopic cervical thyroid tissue which was involved by fibrosing Hashimoto’s thyroiditis and which mimicked metastatic papillary thyroid carcinoma both on fine needle aspiration cytology and biopsy. The patient underwent total thyroidectomy which revealed fibrosing Hashimoto’s thyroiditis, but no carcinoma. The entire…[Read more]