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Pace Kramer posted an update 7 months, 4 weeks ago
Entomopathogenic nematodes are parasitic organisms with an exceptional capacity to infect rapidly and efficiently a wide range of insect species. Their distinct pathogenic properties have established entomopathogenic nematodes as supreme biocontrol agents of insects as well as excellent models to simulate and dissect the molecular and…[Read more]
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Aarup Horton posted an update 7 months, 4 weeks ago
facilitate individualized treatment of SLE immune thrombocytopenia.Previous evidence suggests a link between attention deficit hyperactivity disorder (ADHD) symptoms and disordered eating behaviours; however, the direction of the causal association remains unclear. Building on our previous research, we aimed to examine the longitudinal association…[Read more]
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Buckner Horn posted an update 7 months, 4 weeks ago
Conclusions Clinical genetic testing identifies a causal variant in one third of pediatric patients with primary DCM. Variant reevaluation significantly decreased the number of variants of uncertain significance, but a large burden of variants of uncertain significance remain. These results highlight the need for periodic reanalysis of genetic…[Read more]
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Clay Conradsen posted an update 7 months, 4 weeks ago
Women in the 20-minVideo group experienced significantly fewer episodes of nocturia and urinary urgency and longer average inter-void interval at each follow-up time point. No significant between-group differences were found for any outcome, except for nocturia at 24 months, when effectiveness favored women in the 20-minVideo group.…[Read more]
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Beyer Miranda posted an update 7 months, 4 weeks ago
Group interventions aimed at increasing coping skills for preventing and mastering of depression may lead to a large and stable reduction in depressive symptoms. A key factor in prevention may be to strengthen patients’ perceived ability to cope with the different symptoms of depression.
Group interventions aimed at increasing coping skills for…[Read more]
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Boswell Vinding posted an update 7 months, 4 weeks ago
Following a similar approach on carvacrol-based derivatives, we investigated the synthesis and the microbiological screening against eight strains of H. pylori, and the cytotoxic activity against human gastric adenocarcinoma (AGS) cells of a new series of ether compounds based on the structure of thymol. Structural analysis comprehended elemental…[Read more]
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Kinney Bjerring posted an update 7 months, 4 weeks ago
When compared to the control larvae fed with uncontaminated-pollen, both CHP and CYP significantly reduced the O. bicornis larval survival and their body mass at all tested concentrations. In contrast, ACT did not affect either larval survival or body mass, but the length of larval stage to cocoon formation was significantly shortened compared to…[Read more]
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Jordan Thygesen posted an update 7 months, 4 weeks ago
Copyright © 2020 Author(s).The symptoms associated with COVID-19 are mainly characterized by a triad composed of fever, dry cough and dyspnea. However, digestive symptoms have also been reported; at first considered as infrequent, they in fact seem to affect (to some extent) more than half of patients. The symptoms are mainly manifested by…[Read more]
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Upchurch Warren posted an update 7 months, 4 weeks ago
Moreover, substitution of mprF in a DAPS strain with mutated mprF resulted in cross-resistance and vice versa. The elevated lysyl-phosphatidylglycerol (L-PG) production, increased positive bacterial surface charges and activated cell wall (CW) synthetic pathways were commonly found in both clinical isolates and laboratory-developed mutants that…[Read more]
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Wilder Rasch posted an update 7 months, 4 weeks ago
Introduction Chemical burns are comparably rare but often result in full-thickness skin defects with frequent involvement of underlying structures. Hands are the most commonly affected injury site and impaired functional outcome is common. We present a case of an unusual chemical burn to the dorsum of the hand of a child secondary to application…[Read more]
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Rush Leth posted an update 7 months, 4 weeks ago
Our results indicate that an acidic environment is essential for CARDS toxin retrograde transport to endoplasmic reticulum. Moreover, retrograde transport facilitates toxin clipping and is required to induce vacuole formation. Additionally, toxin-mediated cell vacuolation is strictly dependent on the function of vacuolar type-ATPase.The shift in…[Read more]
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Beach Tobiasen posted an update 7 months, 4 weeks ago
SUMMARY Prenatal diagnostic genetic testing through amniocentesis or chorionic villus sampling can be offered to every patient who wants to learn genetic information about their fetus. Cytogenetic testing, such as microarray is a first tier test to assess cause for these conditions and can provide meaningful answers. When a gastrointestinal…[Read more]
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Whitehead Pape posted an update 7 months, 4 weeks ago
o maximize coverage and intake adherence in programs using SQ-LNS.
The enhanced IYCF-SQ-LNS intervention using the existing health care delivery platform was associated with a reduction in prevalence of anemia and improvement in mean hemoglobin. At endline among the subpopulation receiving ≥3 mo of SQ-LNS, their LAZ, WAZ, and hemoglobin i…[Read more]
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Salas Winkler posted an update 7 months, 4 weeks ago
An amendment to this paper has been published and can be accessed via a link at the top of the paper.A hospital-based cross-sectional study in SIGES project was conducted during 2016.5-2017.5 in West China Hospital. It was aimed to observe the prevalence of atrophic gastritis (AG) in southwest China, and assess the diagnostic strength of serum…[Read more]
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Lindberg Todd posted an update 7 months, 4 weeks ago
The emergence of a novel strain of betacoronavirus, SARS-CoV-2, has led to a pandemic that has been associated with over 700,000 deaths as of 5th August 2020. Research is ongoing around the world to create vaccines and therapies to minimise rates of disease spread and mortality. Crucial to these efforts are molecular characterisations of…[Read more]
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Konradsen Mccormick posted an update 7 months, 4 weeks ago
Iron is an essential component for growth and development. Despite relative abundance in the environment, bioavailability of iron is limited due to oxidation by atmospheric oxygen into insoluble ferric iron. Filamentous fungi have developed diverse pathways to uptake and use iron. In the current study, a putative iron utilization gene cluster…[Read more]
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Sonne Lu posted an update 7 months, 4 weeks ago
Background Great advances have been made for the treatment of urothelial carcinoma by the introduction of checkpoint inhibitors (CPI). Single-agent immunotherapy with CPIs has been approved for patients with metastatic or locally advanced inoperable urothelial carcinoma who have either progressed during or after platinum-based chemotherapy or who…[Read more]
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Mcgowan Meadows posted an update 7 months, 4 weeks ago
We found that taking SG significantly reduced the depressive symptoms assessed by HAMD-24 and improved cognitive functions assessed by MoCA in PSD patients. Furthermore, at baseline, PSD patients showed decreased dALFF in the right precuneus and increased dFC between the right precuneus and left angular gyrus, compared with HC. After intervention,…[Read more]
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Svenningsen Griffith posted an update 7 months, 4 weeks ago
Spinal high mobility group box 1 protein (HMGB1) plays crucial roles in arthritis-induced pain; however, the involvement of peripheral HMGB1 has not been examined previously. In this study, we addressed the role of peripheral HMGB1 and explored if sex contributes differentially to nociception in arthritis. We found Hmgb1 expression to be elevated…[Read more]
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Olsen Gillespie posted an update 7 months, 4 weeks ago
Human carbonic anhydrase IX (hCA IX) is a promising target for the development of potential anticancer agents. In the current study, pharmacophore and 3D-QSAR models have been developed using SLC-0111 derivatives. The developed models have been further utilized for the virtual screening process to develop potent hCA IX inhibitors. Thirteen…[Read more]
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