• Herbert Hall posted an update 8 months ago

    We advocate administering dexrazoxane during cancer treatment to limit the cardiotoxic effects of anthracycline chemotherapy. © The Author(s). 2019.Introduction Assessment of cardiac function after treatment for breast cancer relies on interval evaluation of ventricular function through echocardiography. Women who undergo mastectomy more…[Read more]

  • Fitzpatrick Groth posted an update 8 months ago

    Retinoblastoma (RB) outcomes in Thailand are unfavorable compared to those of developed countries. This study aims to determine whether the clinical outcomes of patients with RB significantly improved after the implementation of new therapeutic approaches as well as which clinical factors affect survival and globe-saving outcomes.

    The…[Read more]

  • Rafferty Lowry posted an update 8 months ago

    We find that classifiers selected by Bayesian optimization for in-hospital mortality can outperform those selected by grid search or random sampling. However, in contrast to previous research 1) Bayesian optimization is not more efficient in selecting classifiers in all instances compared to grid search or random sampling-based methods and 2) we…[Read more]

  • Sunesen Doyle posted an update 8 months ago

    Heterozygous R140 mutations in the IDH2 (isocitrate dehydrogenase 2) gene are responsible for the severe inborn metabolic disorder known as D-2-hydroxyglutaric aciduria type II. The results of treating two children with D2HGA2, one of whom had severe dilated cardiomyopathy, using the enasidenib, a selective IDH2 enzyme inhibitor, are presented…[Read more]

  • Kirk Leslie posted an update 8 months ago

    Enablers for people with Parkinson’s disease (PD) participating in aquatic physiotherapy have been identified, and exercise improves health-related quality of life (HRQoL) but it is unclear whether all enablers and barriers for aquatic physiotherapy specific to the PD population have been explored.

    To describe HRQoL in people with PD who…[Read more]

  • A noteworthy difference in FT4 levels was observed in MHNW participants compared to metabolically healthy or unhealthy obese subjects, a statistically significant finding (P<0.0001) that remained true even after controlling for confounding variables. Obesity phenotypes exhibited no discernible variation in TSH levels (P=0.260). Considering age as…[Read more]

  • Kusk Erickson posted an update 8 months ago

    With the increase of infections due to multidrug resistant bacterial pathogens and the shortage of antimicrobial molecules with novel targets, interest in bacteriophages as a therapeutic option has regained much attraction. Before the launch of future clinical trials, in vitro studies are required to better evaluate the efficacies and potential…[Read more]

  • Maxwell Warming posted an update 8 months ago

    8%) nodes had developed into suspicious LNs after a median follow-up of 44 months. Loss of the fatty hilum and peripheral or diffusedly increased vascularity were more likely to be linked to persistent suspicious LNs (P = .02 and .04, respectively). Suspicious LNs with echogenic foci but a lack of other abnormal features were more frequently f…[Read more]

  • Erickson Finnegan posted an update 8 months ago

    Loss of GbsR or OpcR de-represses opuB and opuC transcription, respectively. With respect to the osmotic control of opuB and opuC expression, we found that this environmental cue operates independently of the OpcR and GbsR regulators. When assessed over a wide range of salinities, opuB and opuC exhibit a surprisingly different transcriptional…[Read more]

  • Vest Feddersen posted an update 8 months ago

    In conclusion, the results indicated that isoflurane suppressed LIRI by inhibiting the activation of NF-κB and the induction of cell apoptosis.COVID-19 pandemic is a reality. This study extracted information from a case in Italy and a case in South Korea during COVID-19 pandemic. Epidemic threat evolved differently in Italy compared to that in…[Read more]

  • Hester Quinn posted an update 8 months ago

    The frequency of patients with HV > 1 SD was higher (p = 0.025) among patients with adherence >90%. The best model to predict the height gain(cm) reaching an adjusted R squared of 0.489 involved percentage of adherence, Tanner stage, pretreatment HV, dose of rhGH, and whether the treatment was initiated before or after puberty.

    Adherence…[Read more]

  • Beach George posted an update 8 months ago

    Importance Nonalcoholic steatohepatitis (NASH) is the inflammatory subtype of nonalcoholic fatty liver disease (NAFLD) and is associated with disease progression, development of cirrhosis, and need for liver transplant. Despite its importance, NASH is underrecognized in clinical practice. Observations NASH affects an estimated 3% to 6% of the US…[Read more]

  • Norman Diaz posted an update 8 months ago

    6 Pa along the free margin, with WSS progressively decreasing towards the belly. During diastole, the aortic side of the fused leaflet exhibited the highest diastolic maximum principal stress, up to 322 kPa within the attachment region. Systematic comparison with ground-truth non-invasive MRI can improve the computational model ability to…[Read more]

  • Penn Moser posted an update 8 months ago

    The rolled Al-2Fe-0.3Co alloy exhibits the highest thermal conductivity, which is about 225 W/(m·K), approximately 11 % higher than the as-cast Al-2Fe sample. The ultimate tensile strength (UTS) and elongation (EL) of as-cast Al-2Fe-0.5Co (UTS 138 MPa; EL 22.0 %) are increased by 35 % and 69 %, respectively, compared with those of unmodified…[Read more]

  • Steele McGinnis posted an update 8 months ago

    This paper studies the convective heat transfer of a hybrid nanofluid in the inclined channel, whose walls are both heated by the uniform heat flux. The governing ordinary differential equations are made nondimensional and solved analytically, in which explicit distributions of velocity, temperature and pressure are obtained. The effects of flow…[Read more]

  • Rode Crowder posted an update 8 months ago

    Objective To investigate the computed tomography(CT)imaging features of IgG4-related kidney disease(IgG4-RKD).Methods The clinicopathological and imaging data of 36 IgG4-RKD patients(including 26 cases of renal parenchyma,10 cases of renal pelvis,24 cases of double kidney or multiple lesions,and 12 cases of single focus)were retrospectively…[Read more]

  • Stevens Mcclain posted an update 8 months ago

    3, 95% CI 1.26-67.74) and meconium stained amniotic fluid (aOR 2.1, 95% CI 1.10-3.85). Parturients who underwent re-suturing had significantly higher rates of postpartum hemorrhage (78.5% vs. 11.4%) blood transfusions (36.2% vs. 1.3%), puerperal fever, and longer hospitalizations (P less then 0.01 for all). Conclusion In our population, early…[Read more]

  • Wooten Murdock posted an update 8 months ago

    This review is tailored to outline the known effects of the current anti-diabetic drugs, anti-inflammatory therapies, and natural compounds on inflammation, which mitigate HF progression in diabetic populations.Metabolic syndrome is associated with hypercholesterolemia, cardiac remodeling, and increased susceptibility to ventricular arrhythmias.…[Read more]

  • Palmer Reeves posted an update 8 months ago

    Alzheimer’s disease (AD) is the most common age-related progressive neurodegenerative disease, characterized by a decline in cognitive function and neuronal loss, and is caused by several factors. Numerous clinical and experimental studies have suggested the involvement of gut microbiota dysbiosis in patients with AD. The altered gut microbiota…[Read more]

  • Yde Malloy posted an update 8 months ago

    This article reviews four emerging endovascular hemorrhage control and extracorporeal perfusion techniques for management of trauma patients with profound hemorrhagic shock including hemorrhage-induced traumatic cardiac arrest. These include resuscitative endovascular balloon occlusion of the aorta (REBOA), selective aortic arch perfusion (SAAP),…[Read more]

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