• Marcher Houghton posted an update 8 months ago

    This article presents the case of an accidental transdermal opioid intoxication in a paramedic. During an ambulance flight mission for patient repatriation several ampules containing opioids were broken unnoticed inside the ampule kit in the outside pocket of the work trousers of the paramedic. He developed the typical clinical picture of opioid…[Read more]

  • Pallesen Mann posted an update 8 months ago

    Prediction of the dynamics of new SARS-CoV-2 infections during the current COVID-19 pandemic is critical for public health planning of efficient health care allocation and monitoring the effects of policy interventions. We describe a new approach that forecasts the number of incident cases in the near future given past occurrences using only a…[Read more]

  • Morton Secher posted an update 8 months ago

    INTRODUCTION A comprehensive characterisation of the tumour microenvironment is lacking in neuroendocrine tumours (NETs), where programmed cell death-1 receptor-ligand (PD-1/PD-L1) inhibitors are undergoing efficacy testing. OBJECTIVE We investigated drivers of cancer-related immunosuppression across NETs of various sites and grade using…[Read more]

  • Bach Thorpe posted an update 8 months ago

    Two studies conducted during the 2016 presidential campaign examined the dynamics of the objectivity illusion, the belief that the views of “my side” are objective while the views of the opposing side are the product of bias. In the first, a three-stage longitudinal study spanning the presidential debates, supporters of the two candidates…[Read more]

  • Aguirre Mcmillan posted an update 8 months ago

    91% had an incident, low-impact fracture. Mean T-score BMD was - 1.09 ± 1.53 for the spine, - 1.08 ± 1.02 for the femoral neck, and - 0.72 ± 0.96 for the total hip. Mean spine TBS was 1.320 ± 0.10. We found a positive association between hs-CRP and BMD at all sites, and between hs-CRP and the TBS, but none of these associations were significa…[Read more]

  • Zimmerman Eskesen posted an update 8 months ago

    Aberrations in membrane trafficking pathways have profound effects in cellular dynamics of cellular sorting processes and can drive severe physiological outcomes. Sorting nexin 27 (SNX27) is a metazoan-specific sorting nexin protein from the PX-FERM domain family and is required for endosomal recycling of many important transmembrane receptors.…[Read more]

  • Sweeney Abildtrup posted an update 8 months ago

    Psychological morbidity in inflammatory bowel disease is common with significant impact on quality of life and health outcomes, but factors which predict the development of psychological morbidity are unclear.

    To undertake a systematic literature review of the predictors of psychological morbidity in patients with inflammatory bowel…[Read more]

  • Skov Dillard posted an update 8 months ago

    Univariable analysis revealed intraepithelial CD8+ cell density as the strongest predictor of endometrial cancer recurrence; multivariable analysis confirmed this was independent of pathologic factors and molecular subgroup. Exploratory analysis suggested this association was not uniform across molecular subgroups, but greatest in tumors with…[Read more]

  • Pallesen Kang posted an update 8 months ago

    Breast cancer is the second leading cause of death in women above 60 years in the US. Screening mammography is recommended for women above 50 years; however, 22% of breast cancer cases are diagnosed in women below this age. We set out to develop a test based on the detection of cell-free RNA from saliva. To this end, we sequenced RNA from a pool…[Read more]

  • Wynn McKenna posted an update 8 months ago

    Our results provide new insights into the patterns of brain evolution among animals that live under extreme conditions.The evolutionary history of organisms with poor dispersal abilities usually parallels geological events. Collisions of the Indian and Arabian plates with Eurasia greatly changed Asian topography and affected regional and global…[Read more]

  • McMillan Dickens posted an update 8 months ago

    The Thai medical application for patient triage, namely Triagist, is an mHealth application designed to support the pre-hospital process. However, since the functions of the application that are necessary for the pre-hospital process have been found not to be fully developed, the addition of a back-end system has been considered to increase its…[Read more]

  • Irwin Bonde posted an update 8 months ago

    The genuine Chinese medicinal (GCM), also known as Dao-di Herbs, is a synonym for high quality Chinese medicinal materials, which has been established in thousands of years of clinical practice and is a comprehensive standard for evaluating the quality of Chinese medicinal materials. The newest data from the Fourth National Survey of Chinese…[Read more]

  • Compton Carlsson posted an update 8 months ago

    Protein phosphatases, by counteracting protein kinases, regulate the reversible phosphorylation of many substrates involved in synaptic plasticity, a cellular model for learning and memory. A prominent phosphatase regulating synaptic plasticity and neurologic disorders is the serine/threonine protein phosphatase 1 (PP1). PP1 has three isoforms…[Read more]

  • Schwartz Franks posted an update 8 months ago

    A delivery service using unmanned aerial vehicles (UAVs) has potential as a future business opportunity, due to its speed, safety and low-environmental impact. To operate a UAV delivery network, a management system is required to optimize UAV delivery routes. Therefore, we create a routing algorithm to find optimal round-trip routes for UAVs,…[Read more]

  • Rahbek McGarry posted an update 8 months ago

    to deepen the understanding and considerations of cause-effect pathways between human activities and changes of ecosystem state through the adoption of targeted cumulative effects assessments.

    Airway remodeling, as many other factors, may lead to lung function decline and irreversible airflow obstruction (IRAO) in asthma. This study was…[Read more]

  • Bryan Stage posted an update 8 months ago

    Hemangioma is a benign tumor made up of blood vessels and typically occurs as a slightly elevated purplish or reddish area of skin. Hemangioma is mostly found superficially; subcutaneous hemangioma in the nasal dorsum is rare.

    In West Nusa Tenggara Regional Hospital, the authors found two cases of subcutaneous hemangioma in patients of…[Read more]

  • Davis Dalton posted an update 8 months ago

    ersensitivity and hyposensitivity.BACKGROUND Chondroblastoma (CB) is a rare locally aggressive bone tumor that commonly occurs in the epiphysis or apophysis of long bones. Although surgical treatment of CB carries potential risk for physeal or articular cartilage damage, risk factors for joint degeneration have not been well described. In…[Read more]

  • Vittrup Shapiro posted an update 8 months ago

    Melon necrotic spot virus (MNSV) was detected in field-grown Cucumis melo (rockmelon) and Citrullus lanatus (watermelon) plants in the Sunraysia district of New South Wales and Victoria, Australia, in 2012, 2013, and 2016, and in two watermelon seed lots tested at the Australian border in 2016. High-throughput sequencing was used to generate near…[Read more]

  • Mcclure Daly posted an update 8 months ago

    Although doubling the field dose (720 + 480 g ha-1) improved (5-22%) the control of these weeds in the field, split applications of both premix and tank mix provided the best control levels (≤70%), but premix treatments maintained control levels above 85% for longer (120-d). No antagonism between glyphosate and 2,4-D was found. The addition of 2…[Read more]

  • Li McCain posted an update 8 months ago

    INTRODUCTION AND OBJECTIVES Lack of consensus regarding how best to define treatment response hinders translation from trials to the clinic. These post hoc analyses examine three commonly used response criteria in six trials of lisdexamfetamine dimesylate (LDX) in children and adolescents with attention-deficit/hyperactivity disorder (ADHD).…[Read more]

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