• The need for effective candidates as cytotoxic drugs that at the same time challenge cancer multidrug resistance encouraged a search for these in plants of central Argentina. Bioassay-guided fractionation of the cytotoxic extract from Dimerostemma aspilioides led to the isolation of the germacranolide tomenphantin A (1), along with three new…[Read more]

  • Emotional Durability in Small Woman Sports athletes.

    The odds of having preterm delivery was higher for nulliparous patients and those with lower intraoperative diastolic pressure.

    Our findings confirm what has been previously reported regarding the association of nulliparity with preterm delivery. Additionally, this study highlights…[Read more]

  • Raun Gunn posted an update 8 months, 1 week ago

    4 (6.4-8.7) versus 9.5 (8.1-11.0); adjusted hazard ratio (HR) (95% CI) = 0.81 (0.60-1.09), P = 0.17. Patients exposed to SPS did not experience a higher rate of adverse GI events in the year after SPS initiation versus the year before SPS initiation; P-value for parallel trend = 0.87. Patients on-CPS also did not show an increased risk of adverse…[Read more]

  • Decision-makers are advised to attach importance to the efficiency of operation management and consider the impact of multiple factors on the change in productivity.

    The medical environment and resources have been greatly improved due to the expansion of the sample hospitals, but the technical efficiency value indicates that the operation…[Read more]

  • Oral squamous cell carcinoma (OSCC) is one of the most common type of head and neck squamous cell carcinoma and one of the multifactorial process that consists of most contributing factors such as tobacco smoking, chewing and alcohol consumption that altered the intracellular environment. Recent studies have shown relevance of Toll like receptor…[Read more]

  • 5 cm laterally at the level of point A. In two initial applications 55 and 54 cc of high-risk clinical target volumes (HRCTV) were treated, and 90% of the HRCTV was covered by 96% and 97% of prescribed doses, respectively. Additionally, the needles guided by the template helped in sculpting the dose from bladder and rectum. Conclusions We have…[Read more]

  • Heavy alcohol consumption is a common cause of acute pancreatitis; however, alcohol abuse does not always result in clinical pancreatitis. As a consequence, the factors responsible for alcohol-induced pancreatitis are not well understood. In experimental animals, it has been difficult to produce pancreatitis with alcohol. Clinically, alcohol use…[Read more]

  • Factor Analysis is used to extract four contaminant indicators, which suggests the local air suffers sulfur oxides pollution the most. The air quality index of the eight study sections calculated are all below 60, ranging from 24 to 58. It indicates that coal fire air pollution is in the medium-to-severe stage. By Canonical Correlation Analysis,…[Read more]

  • Congenital Diaphragmatic Hernia (CDH) is due to a defect in the diaphragm and is usually detected soon after birth. However, in rare cases, asymptomatic CDHs can be missed and present later in life. Late-presentation CDH can be misdiagnosed as tension pneumothorax leading to iatrogenic complications. We report a case of a 10-year-old boy who…[Read more]

  • 85 points with the most significant improvement in the threshold subcomponent. There were no adverse outcomes from intranasal PRP injections. Conclusion PRP appears safe for use in the treatment of olfactory loss, and preliminary data suggest possible efficacy, especially for those with moderate yet persistent loss. Further studies will help…[Read more]

  • Yildiz Han posted an update 8 months, 1 week ago

    Scalable fabrication concepts of 3D kidney tissue models are required to enable their application in pharmaceutical high-throughput screenings. Yet the reconstruction of complex tissue structures remains technologically challenging. We present a novel concept reducing the fabrication demands, by using controlled cellular self-assembly to achieve…[Read more]

  • Sistermanns M, Kowall B, Hörnig M et al. Motion Artifact Reduction in Contrast-Enhanced Dual-Energy Mammography – A Multireader Study about the Effect of Nonrigid Registration as Motion Correction on Image Quality. Fortschr Röntgenstr 2021; DOI 10.1055/a-1388-7712.Smoking tobacco is the most important and potentially modifiable risk factor for can…[Read more]

  • Tissue factor pathway inhibitor 2 (TFPI2) is a novel serum biomarker that discriminates ovarian clear cell carcinoma (CCC) from borderline ovarian tumors (BOTs) and non-clear cell epithelial ovarian cancers (EOCs). Here, we examined the performance of TFPI2 for preoperative diagnosis of CCC.

    Serum samples were obtained preoperatively from…[Read more]

  • Active bleeding within the gastrointestinal (GI) system is arrested by a topical hemostatic powder, which creates an adhering barrier. The Food and Drug Administration (FDA) in the United States has formally recognized Hemospray as the pioneering hemostatic powder to receive their approval. Gastrointestinal bleeding management is increasingly…[Read more]

  • Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive multiple congenital malformation and intellectual disability syndrome resulting from variants in DHCR7. Auditory characteristics of persons with SLOS have been described in limited case reports but have not been systematically evaluated. The objective of this study is to describe the…[Read more]

  • CSA was linked to greater disorganization scores that were associated with higher scores of emotion dysregulation. Emotion dysregulation was in turn associated with increased severity of dissociation symptoms in preschool children one year later. LIMITATIONS Given that attachment and emotion dysregulation were both assessed at T1, the temporal…[Read more]

  • Additionally, we observed the pulmonary expression of 44 previously unannotated miRNAs. The sequencing of these fetal lung samples also provides a baseline resource against which aberrant samples can be compared.

    During the first COVID-19 pandemic outbreak, a new triage concept had to be implemented for patients with retinal diseases having a…[Read more]

  • Radioembolization with yttrium-90 (Y-90) is an effective locoregional therapy for primary and metastatic liver tumors, but its use is restricted or contraindicated for patients with elevated lung shunt fraction (LSF) because of an increased risk of developing pulmonary adverse events, including but not limited to radiation pneumonitis. Elevated…[Read more]

  • This study aimed to examine how anxiety related to different styles of coping during the COVID-19 pandemic and how these relationships were moderated by the cultural orientations of individualism/collectivism and a person’s sense of meaning in life. A sample of 849 participants from Georgia completed an online survey during the final stage of…[Read more]

  • y.

    The prognosis of acute ischemic stroke is related to collateral circulation, which is different with different pathogenesis.

    To explore the prognosis of acute large atherosclerotic (LAA) cerebral infarction with different pathogenesis by assessing the establishment of collateral circulation.

    108 patients with acute LAA…[Read more]

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